2008-2010年绵阳地区献血人群HBV流行情况分析  

Investigation on the status of HBV prevalence among blood donors in Mianyang,2008-2010

作　　者：曹汝安 文秀琼[1] 黄梅[1] 王憬惺[2] 刘鱼[2] 何苗[2] 曾沛斌[2] 

机构地区：[1]绵阳市红十字中心血站,四川绵阳621000 [2]中国医学科学院北京协和医学院输血研究所

出　　处：《中国输血杂志》2015年第7期820-822,共3页Chinese Journal of Blood Transfusion

摘　　要：目的统计分析绵阳地区献血人群2008年1月-2010年12月HBV的流行率、新发率,评估HBV在该地区的流行情况。方法收集2008年1月-2010年12月100 429人次献血者人口统计学资料、2轮第3代ELISA试剂初筛和确证数据。分别计算初次献血者和重复献血者的HBV流行率,利用文献报道的新发率评估模型,评估重复献血人群的新发率。结果 2008年1月-2010年12月绵阳地区初次献血和重复献血人群的HBV流行率依次为0.97%和0.04%,重复献血人群中的HBV感染新发率为0.32%。结论绵阳地区献血人群具有较高的流行率和新发率,可能引起较高的HBV输血残余风险,应考虑采用第4代ELISA初筛试剂和核酸检测(NAT)降低该地区的HBV对血液安全的影响。Objective To analyze the prevalence and incidence rates of HBV among blood donors in Mianyang from January 2008 to December 2010. Methods Demographic information were collected from 100 429 donations which underwent two rounds of third generation ELISA kits and confirmatory testing. The HBV prevalence and incidence rates on first and repeat donors were calculated using the reported incidence evaluation model. Results During the study period,the prevalence rates among first and repeat donors were 0. 97% and 0. 04%,respectively. The HBV incidence rate on repeat donors was 0. 32%. Conclusion Relative high HBV prevalence and incidence rates in Mianyang may lead to high HBV transfusion residual risk,and the fourth generation ELISA screening assays and NAT testing were suggested to be implemented reducing the impact of HBV on blood safety in Mianyang.

关 键 词：绵阳地区 献血人群 HBV 流行率 新发率 

分 类 号：R446[医药卫生—诊断学] R373.21[医药卫生—临床医学]