临床药学服务模式在癫痫治疗中的实践与评价  

Practice and evaluation of clinical pharmacy service model in epilepsy treatment

作　　者：杨琴琴[1] 林玮玮[2] 王长连[2] 王华燕[3] 

机构地区：[1]福建医科大学药学院,福州350108 [2]福建医科大学附属第一医院药学部,福州350005 [3]福建医科大学附属第一医院神经内科,福州350005

出　　处：《中国临床药理学杂志》2015年第16期1668-1670,共3页The Chinese Journal of Clinical Pharmacology

基　　金：福建省自然科学基金资助项目(2013J01370);福建医学创新基金资助项目(2014-CXB-13);福建医科大学教授基金资助项目(JS10012)

摘　　要：目的探讨临床药学服务在癫痫药物治疗中的作用。方法将癫痫患者随机分为试验组和对照组,试验组接受临床药学服务干预,对照组不予以干预,随访8个月。以临床疗效、癫痫知识知晓率、依从性、用药合理性等为指标,评价临床药学服务的作用。结果试验组的临床疗效(癫痫发作控制总有效率)、癫痫知识知晓率、依从性(无漏药、良好生活习惯、定期复查肝功能血常规)及用药合理性(定时服药、等间隔用药)均优于对照组(P<0.05)。结论临床药学服务对提高癫痫治疗的临床疗效、癫痫知识知晓率、依从性及用药合理性具有重要意义。Objective To explore the effectiveness of clinical pharmacy services in epilepsy drug treatment. Methods We divided patients into experimental group and control group. Patients in experimental group were treated with clinical pharmacy services. And patients in control group were not. In the following 8 months, we interviewed them periodically. We evaluated the effect of clinical pharmaceutical service by metrics such as curative effect,awareness of knowledge about epilepsy,compliance,the rationality of drug use. Results Experimental group were significantly superior to control group（ P〈0. 05） in metrics like clinical curative effect（ epilepsy controlled rate）, awareness of knowledge about epilepsy, compliance（ non- occurrence of drug leakage,good living habits,regularly liver function and blood tests）,and the rationality of drug use（ taking drugs regularly,and with equal time- intervals）. Conclusion Clinical pharmacy services can significantly improve the clinical curative effect,epilepsy drug knowledge awareness,compliance,and the rationality of drug use in patients with epilepsy.

关 键 词：癫痫 临床药学服务 实践与评价 

分 类 号：R969.3[医药卫生—药理学] R971.6[医药卫生—药学]