中、重度颅脑损伤患者垂体激素、甲状腺激素水平变化与预后相关性研究  

The study on the relationship between pituitary hormones,thyroid hor-mone levels and prognosis of the patients with moderate and severe cran-iocerebral injury

作　　者：陶裕川[1] 

机构地区：[1]四川省宜宾市第二人民医院神经外一科,四川宜宾644000

出　　处：《中国现代医生》2015年第24期8-10,共3页China Modern Doctor

摘　　要：目的探讨中、重度颅脑损伤垂体激素、甲状腺激素水平变化与预后之间的关系。方法选取2011年12月～2014年6月我院临床收治的中重度颅脑损伤患者220例为研究对象，按照患者的伤情以及预后情况进行分组比较，研究患者激素水平的变化与伤情严重程度及预后的关系。结果①中度颅脑损组患者的PRL、FSH、TT3、FT等均明显优于重度颅脑损组患者，差异均具有高度统计学意义（P〈0．01）；②存活组患者的PRL、FSH、TT3、FT3和FT4等均明显优于死亡组（P〈0．01）。结论颅脑损伤患者损伤程度越重，预后越差，患者的PRL、FSH指标水平越高，TT3、FT3指标水平越低，PRL、FSH、TT3、FT3可用于判断颅脑损伤患者的病情和预后。Objective To study the relationship between pituitary hormones, thyroid hormone levels and prognosis of the patients with moderate and severe craniocerebral injury. Methods 220 patients with moderate and severe cranio- cerebral injury from December 2012 to June 2014 were selected as research objects.They were compared with injury and prognosis. The relationship between pituitary hormones, thyroid hormone levels and prognosis of the patients were studied. Results①The PRL, FSH, TT3, FT3 of moderate craniocerebral injury patients were significantly better than those of severe craniocerebral injury patients（P〈0.01）; ②The PRL, FSH, Tt3, F33 and FT4 of the survival group patients were significantly better than those of death group（P〈0.01）. Conclusion Patients with more severe craniocerebral injury degree of injury, the worse the prognosis, patients with PRL, FSH index level is higher and with TT3, FT3 index level is lower, PRL, FSH,TT3, FT3 can be used to determine the severity and prognosis of patients with eraniocerebral in- jury.

关 键 词：颅脑损伤 垂体激素 甲状腺激素 预后 相关性 

分 类 号：R651.1[医药卫生—外科学]