双源CT迭代重建算法联合低管电压及低浓度对比剂冠状动脉成像的研究  

Research based on dual-source CT iterative reconstruction algorithm combined with low tube voltage and low concentration contrast agent imaging for coronary artery

作　　者：顾浩 李嘉鹏[2] 贾玉柱[2] 

机构地区：[1]浙江省宁波市第二人民医院放射科,浙江宁波315000 [2]浙江省立同德医院放射科,浙江杭州310000

出　　处：《中国医药导报》2015年第25期116-120,共5页China Medical Herald

基　　金：浙江省中医药科学研究基金计划项目(2012Z B001)

摘　　要：目的探讨第二代双源（炫速双源）CT冠状动脉成像中，应用迭代重建算法与等渗低浓度对比剂及低电压技术时的图像质量及辐射剂量。方法收集宁波市第二人民医院及浙江省立同德医院2014年3月。2015年3月的80例冠心病患者（BMI〈30kg／m^2,心率〈65次，min）按CT号码的单双号分成AiB两组，每组各40例。两组均采用冠状动脉双源CT前瞻性大螺距扫描，A组采用低电压和低浓度对比剂及迭代重建（SAFIRE）进行冠状动脉CT检查；B组采用常规电压及常规浓度对比剂及滤波反投影（FBP）对冠状动脉进行重建。两位有经验的心血管系统诊断医师采用双盲法，以5分法评定系统对冠状动脉16段分支血管成像质量进行评分，对两组有效辐射剂量、平均CT值、图像噪声、信噪比（SNR）、对比信噪比（CNR）、图像质量评分进行比较。采用t检验比较计量资料组间差异。结果两组患者一般资料、辐射剂量、图像质量比较，除了辐射剂量中的管电流具有统计学差异（P〈0．05）外，其余差异均无统计学意义（P〉0．05）。两组CNR、SNR、CT值比较差异均无统计学意义（P〉0．05）。结论在BMI〈30kg/m^2，心率〈65次／min条件下，前瞻性大螺距扫描、迭代重建算法和低浓度非离子型造影剂及低管电压综合的多种技术进行冠状动脉CTA检查时，可以使辐射剂量明显降低且对冠状动脉诊断的准确性无明显影响。Objective To evaluate the image quality and radiation dosage of dual-source CT iterative reconstruction algorithm combined with low tube voltage and low concentration contrast agent imaging for coronary artery. Methods From March 2014 to March 2015, 80 patients （ BMI 〈 30 kg/m^2, heart rate 〈 65 times/min） from the Second People＇s Hospital and Tongde Hospital of Zhejiang Province were enrolled into two groups （group A, group B） based on odd or even CT number in this study,40 cases in each group. Dual-source CT large pitch imaging scanning technique for coronary artery was applied to all patients. Patients in group A were scanned with low voltage and low concentration of contrast agent and ite, rative reconstruction （SAFIRE） for coronary artery CT examination;while patients in group B were scanned with normal regular voltage and concentration of contrast medium and filter back projection place （FBP） for coronary artery reconstruction. Image quality of 16 coronary artery branches were scored with 5 points method assessment system by two experienced cardiovascular diagnosis physicians, and the differences of the effective radiation dose, the average CT Value and image noise, the signal-to-noise ratio（SNR）, contrast signal to noise ratio （CNR）, image quality scores were compared between two groups, using double blind evaluation system. T test was performed between measurement data sets. Results Statistical differences was found in the tube current radiation dose （t = 0.148, P 〈 0.05）. No statistical differences was found in the general information, radiation dose and image quality （P 〉 0.05）. CNR, SNR, CT value showed no statistical differences between the two groups （P 〉 0.05）. Conclusion The radiation dose decreases obviously when prospective big pitch scanning technology, the iterative reconstruction, technology of the low concentration of contrast medium and low voltage coronary CTA examination performed under the condition of BMI 〈 30 kg/m^2, heart rate 〈 65 ti

关 键 词：体层摄影术 X线计算机 冠状动脉血管造影术 

分 类 号：R814.42[医药卫生—影像医学与核医学]