腹腔镜下子宫切除术对患者免疫功能的影响及远期预后分析  

Analysis of the effect of laparoscopic hysterectomy on immune function in patients and long-term prognosis

作　　者：徐丹[1] 洛若愚[1] 

机构地区：[1]武汉大学人民医院妇产科,武汉430060

出　　处：《中国医学前沿杂志（电子版）》2015年第6期109-112,共4页Chinese Journal of the Frontiers of Medical Science(Electronic Version)

摘　　要：目的探讨腹腔镜下子宫切除术对患者免疫功能及远期预后的影响。方法选择2011年2月至2013年2月本院收治的腹腔镜下子宫切除术患者120例作为观察组,另选择同期行传统开腹子宫切除术的患者98例作为对照组,比较两组患者手术情况,手术前后免疫功能指标变化情况,术中、术后并发症发生情况及远期预后。结果两组患者术中出血量、手术时间、术后排气时间以及住院天数比较差异均具有显著性(P<0.05)。两组患者术前免疫功能指标比较差异无显著性(P>0.05),观察组患者术后白细胞计数、中性粒细胞比率以及C反应蛋白(CRP)水平均低于对照组(P<0.05)。观察组患者术中、术后并发症发生率均明显低于对照组(P<0.05)。观察组患者预后良好,对照组患者出现1例排尿疼痛,切口疝与肠梗阻患者再次手术后恢复。结论腹腔镜下子宫切除术具有损伤小、感染发生率低等特点,同时远期预后较传统开腹手术理想,值得临床推广应用。ObjectiveTo investigate the effect of laparoscopic hysterectomy on immune function in patients and long-term prognosis.Method120 patients treated with laparoscopic hysterectomy in our hospital from February 2011 to February 2013 were selected as observation group. 98 patients treated with traditional open hysterectomy were selected as control group. General situation of operation, changes of the index of immune function before and after operation, intraoperative and postoperative complications, and long-term prognosis of the two groups were compared.ResultDifferences of intraoperative blood loss, operative time, postoperative evacuating time, and hospitalization days between the two groups had no signiifcant （P〈0.05）. There were no significant differences between two groups of patients with preoperative immune function indexs （P〉0.05）. Observation group of patients with postoperative white blood cell count, neutrophils ratio and CRP were lower than control group （P〈0.05）. Intraoperative and postoperative complications in patients with observation group were signiifcantly lower than control group （P〈0.05）. Observation group had good prognosis, and control group had 1 case of urination pain, the patients with incision hernia and intestinal obstruction were recovered after reoperation.ConclusionLaparoscopic hysterectomy has the characteristics of low damage, low incidence of infection, and the long-term prognosis is better than traditional open surgery, worthy of clinical application.

关 键 词：腹腔镜 子宫切除术 免疫功能 

分 类 号：R713.4[医药卫生—妇产科学]