磷霉素氨丁三醇散与诺氟沙星治疗急性泌尿系感染  

Clinical comparison of Fosfomycin ammonia butyl alcohol three powder combined with norfloxacin in treatment of acute urinary tract infection

作　　者：秦大勇[1] 刘生 

机构地区：[1]河南省潢川县人民医院外科,465150 [2]信阳市第一人民医院

出　　处：《中国实用医刊》2015年第17期69-70,共2页Chinese Journal of Practical Medicine

摘　　要：目的 比较磷霉素氨丁三醇散与诺氟沙星治疗急性泌尿系感染的效果.方法 将80例急性泌尿系统感染患者随机分为两组,每组40例.对照组采用诺氟沙星治疗,观察组采用磷霉素氨丁三醇散治疗,观察两组患者的临床疗效,记录两种药物对致病菌的清除率、敏感率耐药率.结果 观察组治疗有效率为92.5％,高于对照组的75.0％,差异有统计学意义（P＜0.05）.观察组细菌清除率、敏感率分别为90.63％、96.88％,均高于对照组的58.09％、80.62％,细菌耐药率为3.12％,低于对照组55.58％,差异有统计学意义（P＜0.05）.结论 磷霉素氨丁三醇散治疗急性泌尿系统感染,细菌耐药性较低,可提高细菌清除率.Objective To compare the effects of fosfomycin ammonia butyl alcohol three powder and norfloxacin on acute urinary tract infection.Methods Eighty patients with acute urinary system infection were selected as the research objects,and were randomly divided into two groups.The patients in the control group were given norfloxacin treatment,and the patients in the observation group were given fosfomycin ammonia butyl alcohol three powder treatment.The clinical effects of the two groups were observed,and the remove rates,sensitive rates and drug resistance rates of the two kinds of drugs were recorded.Results The effective rate of observation group （92.5 %） was higher than that of control group （75 %）,the difference was significant （P 〈 0.05）.The bacterial clearance rate,sensitive rates of the observation group（90.63%,96.88%）were lower than those of the control group（58.09%,80.62%）,the bacterial drug resistance rate（3.12%） was lower than that of the control group（55.58%）,the differences were significant （P 〈 0.05）.Conclusions The bacterial resistance is low that fosfomycin ammonia butyl alcohol three powder in the treatment of acute urinary tract infection.It can increase the clearance rate of bacteria.

关 键 词：急性泌尿系感染 磷霉素氨丁三醇散 诺氟沙星 耐药性 

分 类 号：R978.19[医药卫生—药品]