应用三维多普勒超声定量测量胎盘对高血压孕妇胎儿状态的评估  

Value of quantitative measurement of placenta with three-dimensional power Doppler ultrasonography in pregnant women with pregnancy-induced hypertension

作　　者：杨瑞琦[1] 张嘉玲[1] 朱崇磊[2] 王飞[1] 范丽梅[1] 

机构地区：[1]吉林大学第二医院妇产科, 长春130041 [2]吉林大学第四医院中国第一汽车集团公司职工总医院CT科

出　　处：《中华医学杂志》2015年第31期2551-2553,共3页National Medical Journal of China

基　　金：基金项目：中国博士后科学基金（2014T70298,2013M541316）;吉林省科技厅重点科技攻关项目（20132068SF）

摘　　要：目的 通过三维能量多普勒超声定量测量胎盘,评估妊娠期高血压疾病孕妇胎儿宫内的状态.方法 选取2012年11月至2014年8月间于吉林大学第二医院妇产科临床诊断为妊娠期高血压疾病孕妇50例作为观察组,随机选取相对应孕周孕妇50例作为对照组,应用三维能量多普勒超声定量测量两组胎盘血管化指数（VI）、血流指数（FI）和血管化-血流指数（VFI）.对照组VI、FI、VFI行线性回归分析,计算出不同孕周的均值和95％可信区间.结果 两组胎儿的胎盘VI、FI、VFI检出率均为100％,对照组胎盘VI的线性回归方程为：Y =0.394X-5.358,R2=0.694,P＜0.05;FI的线性回归方程为：Y =0.801X ＋5.61,R2 =0.807,P＜0.05;VFI的线性回归方程为：Y =0.225X-4.148,R2 =0.691,P＜0.05,观察组VI、FI、VFI不同孕周均值和对照组VI、FI、VFI不同孕周均值分别行t检验,均P ＜0.05.结论 对胎盘行三维能量多普勒检查,其VI、FI、VFI随孕周增加而增大,伴发妊娠期高血压疾病胎儿胎盘VI、FI、VFI测值和正常胎儿胎盘的测值间差异有统计学意义,三维能量多普勒超声定量测量胎盘具有自身优势,可对伴发妊娠期高血压疾病胎儿胎盘状态进行评估.Objective To evaluate the intrauterine state of fetuses with pregnancy-induced hypertension （PIH） through quantitative measurement of placenta by three-dimensional power Doppler ultrasonography,and to judge the value of three-dimensional power Doppler in PIH fetuses.Methods A total of 50 pregnant women with PIH in our hospital from November 2012 to August 2014 were enrolled into the observation group,while 50 cases were randomly selected into the control group to match the former group＆#39;s gestational week （GA）.The placental vascularization index （VI）,flow index （FI） and vascularization flow index （VFI） were quantitatively measured by three-dimensional power Doppler ultrasonography in the two groups.SPSS 19 statistics software was used to do the linear regression for the above parameters.And those parameters of the two groups were compared by t test.P 〈 0.05 was deemed significant.Results The detection ratio of fetal placental VI,FI and VFI of the whole 100 cases was 100%.The regression equation of V1 and GA was：Y =0.394X-5.358,R2 =0.694,P〈0.05;the regression equation of FI and GA was：Y =0.801X ＋ 5.61,R2 =0.807,P 〈 0.05;the regression equation of VFI and GA was：Y =0.225X-4.148,R2 =0.691,P〈0.05.t tests showed the differences of the means of placental VI,FI and VFI between the observation group and the eontrol group were statistically significant （all P 〈 0.05）.Conclusions VI,FI and VFI of placenta measured by three-dimensional power Doppler examination increase with the increase of GA,and the means of placental VI,FI and VFI in PIH patients are less than those in normal cases.Quantitative measurement of placenta with three-dimensional power Doppler ultrasound has its own advantages,and can evaluate the status of placenta of PIH fetus accurately.

关 键 词：能量多普勒超声 妊娠期高血压疾病 胎盘 

分 类 号：R445.1[医药卫生—影像医学与核医学] R714.5[医药卫生—诊断学]