火针对脊髓损伤模型大鼠神经功能缺损恢复程度和脊髓神经超微结构的影响  

Effect of Fire Needling on the Recovery of Neurological Deficit and Spinal Nerve Ultrastructure in Model Rats with Spinal Cord Injury

作　　者：王剑歌 李岩[2] 周震[3] 陆军[2] 刘保红[2] 蔡志敏[1] 程素利[1] 周智梁[3] 

机构地区：[1]天津中医药大学,天津300193 [2]天津市公安医院,天津300042 [3]天津中医药大学第二附属医院,天津300150

出　　处：《针灸临床杂志》2015年第7期80-82,F0003,共4页Journal of Clinical Acupuncture and Moxibustion

基　　金：国家自然科学基金项目;编号:81373839;天津市自然科学基金重点项目;编号:13JCZDJC31800

摘　　要：目的:探讨火针对脊髓损伤(SCI)模型大鼠神经功能缺损恢复程度和脊髓神经超微结构的影响。方法:选择SD大鼠,随机分为假手术组、火针治疗组、脊髓损伤对照组与空白对照组,采用改良Allen's法建立急性SCI模型,经火针治疗后,在不同时段运用Basso-Beattic-Bresnahan行为功能评分(BBB运动评分),取材后采用透射电镜进行超微结构观察。结果:电镜下火针治疗组大鼠脊髓损伤节段超微结构改变较脊髓损伤对照组有所减轻,有神经纤维修复再生。BBB评分提示火针治疗组与其他各组均有显著性差异(P<0.05),且火针治疗组评分均高于脊髓损伤对照组。结论:大鼠脊髓损伤后火针治疗可以促进神经功能的恢复。Objective： To nal nerve ultrastructure in observe the influence model rats with spinal groups randomly：a fire needling group, a sham group. Modified Allen＇s method was applied to of fire needling on the recovery of neurological deficit and spicord injury. Methods：Male adult SD rats were divided into four operation group, an injured control group and a normal control prepare the spinal cord injured models. Locomotor function was evaluated by using Basso - Beattic - Bresnahan （BBB） needling therapy. Uhrastructure changes were detected scale at the 1st, 3rd, 7th, 10th and 14th day after fire by electron microscope. Results：Ultrastructure changes of rats in the fire needling group reduced less than those in the injured control group, and the nerve fibers were repaired and regenerated. BBB analysis of variance showed that there was a significant difference between fire needling group and others（P 〈 0.05 ）. The scores on fire needling cured group were higher than others, Con- clusion：Fire needling could promote the recovery of neurological function after spinal cord injury.

关 键 词：火针 脊髓损伤 超微结构 实验研究 

分 类 号：R246.6[医药卫生—针灸推拿学]