Preparation and Chiral Recognition of Thermosensitive Poly（N-isopropylacrylamide） Microgels Containing Modified L-Phenylalanine Groups  

作　　者：CHEN Jiaojiao YIN Yue FU Hongjun LI Qifeng ZOU Jiwei 

机构地区：[1]State Key Laboratory of Separation Membranes and Membrane Process, School of Environmental and Chemical Engineering [2]Tianjin Key Laboratory of Fiber Modification and Functional Fiber and Textile Division, Tianjin Polytechnic University, Tianjin 300387, P. R. China

出　　处：《Chemical Research in Chinese Universities》2015年第4期664-668,共5页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China（No.20904039） and the Tianjin Research Program of Appli- cation Foundation and Advanced Technology, China（No. 10JCYBJC02900）.

摘　　要：Thermosensitive poly[N-isopropylacrylamide（NIPAM）-co-N-acryloyl-L-phenylalanine ethyl ester （NALPE）] microgels were prepared by the free radical polymerization of NIPAM and chiral monomer, NALPE. Such microgels exhibited spherical shape and favorable monodispersity. Increasing the content of NALPE units would en- hance the average diameter, but decrease the thermosensitivity and volume-phase transition temperatures of the mi- crogels. Compared with PNIPAM microgels, the microgels containing NALPE units performed chiral recognozable capacities for D-phenylalanine and D-tartaric acid, and the enantioselectivity and adsorption capacity of the microgels improved with increasing the temperature and/or the content of NALPE units.Thermosensitive poly[N-isopropylacrylamide（NIPAM）-co-N-acryloyl-L-phenylalanine ethyl ester （NALPE）] microgels were prepared by the free radical polymerization of NIPAM and chiral monomer, NALPE. Such microgels exhibited spherical shape and favorable monodispersity. Increasing the content of NALPE units would en- hance the average diameter, but decrease the thermosensitivity and volume-phase transition temperatures of the mi- crogels. Compared with PNIPAM microgels, the microgels containing NALPE units performed chiral recognozable capacities for D-phenylalanine and D-tartaric acid, and the enantioselectivity and adsorption capacity of the microgels improved with increasing the temperature and/or the content of NALPE units.

关 键 词：Thermosensitive microgel N-ISOPROPYLACRYLAMIDE L-PHENYLALANINE Chiral recognition 

分 类 号：O633.22[理学—高分子化学] TQ922.9[理学—化学]