基于DNA链置换反应的编码器逻辑运算模型研究  

The Research of Encoder Logic Operation Model Based on DNA Strand Displacement Reaction

作　　者：王子成[1,2] 豆根生[3] 叶盟盟 

机构地区：[1]郑州轻工业学院电气信息工程学院,郑州450002 [2]河南省信息化电器重点实验室,郑州450002 [3]河南农业大学理学院,郑州450002

出　　处：《河南师范大学学报（自然科学版）》2015年第4期144-150,共7页Journal of Henan Normal University(Natural Science Edition)

基　　金：国家自然科学基金(U1304620);河南省教育厅科学技术研究重点项目(13A413371)

摘　　要：作为自组装DNA计算领域中一门新技术,DNA链置换反应在分子计算领域得到了广泛的应用.基于自组装DNA计算原理,设计了对应不同逻辑门的DNA分子电路.基于DNA链置换反应机理构建了编码器逻辑电路的分子计算模型.当输入DNA分子信号链时,将不同分子浓度比的DNA分子逻辑门电路混合,借助分子间的特异性杂交反应及分子间链置换反应,最终可输出信号链分子.Visual DSD仿真结果表明了本文设计的编码器逻辑计算模型的可行性与准确性.为拓展分子逻辑电路的应用做出有益的探索.As a new technology and its outstanding advantages in DNA self-assembly computing,DNA strand displacement reaction has been widely used on molecular computing field in recent years.Based on the principle of DNA self-assembly computing,logic circuit models of different logic gates were constructed.And then,the encoder logic operation models were designed according to DNA strand displacement reaction theory.when the DNA signal strands are input with others DNA strands corresponding to different logic gate molecular circuits,the new DNA signals strands can be output after a series of reactions among DNA strands.The simulation results achieved in Visual DSD software show that it is feasible and accurate for the encoder logic design operation model constructed in this paper,which is helpful for the application of molecular logic circuit research.

关 键 词：DNA自组装 DNA链置换反应 编码器 逻辑电路 

分 类 号：TP384[自动化与计算机技术—计算机系统结构]