金荞麦叶发酵茶的抗炎作用研究  

Study on Anti-inflammatory Function of Gold Buckwheat Fermented Tea

作　　者：黄小燕[1] 黄莎[1] 陈庆富[2] 

机构地区：[1]贵州师范大学生命科学学院,贵阳550001 [2]贵州师范大学生命科学学院植物遗传育种研究所,贵阳550001

出　　处：《世界科学技术-中医药现代化》2015年第5期981-984,共4页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：贵州省科技厅国际合作项目(黔科合外G字[2013]7021):金荞麦叶发酵茶的工艺研究与功能评价;负责人:黄小燕;国家燕麦荞麦现代农业产业技术体系荞麦育种岗位专项资金(CARS-08-A4):荞麦育种;负责人:陈庆富;国家自然科学基金委面上项目(31171609):荞麦属植物落粒性相关基因研究;负责人:陈庆富;贵州省科技厅科学技术基金项目(黔科合J字[2012]2268):荞麦标准提取物的制备和抗氧化功能研究;负责人:黄小燕;贵州省科技厅项目(黔科合人才团队[2011]4007):荞麦产业技术科技创新团队;负责人:陈庆富

摘　　要：目的:观察金荞麦叶发酵茶对小鼠急、慢性炎症反应的影响。方法:以二甲苯致耳廓肿模型、角叉菜胶致足趾肿胀模型、醋酸致小鼠腹腔毛细血管通透性增高急性炎症模型、肉芽肿慢性炎症模型评价金荞麦叶发酵茶的抗炎作用。结果:金荞麦叶发酵茶可使二甲苯致小鼠耳廓肿胀率明显下降,能显著降低角叉菜胶致炎后大鼠足跖肿胀,对醋酸致小鼠腹腔毛细血管通透性增高急性炎症有拮抗作用;对慢性炎症肉芽肿的增生也有明显的抑制作用。结论:金荞麦叶发酵茶具有防治急、慢性炎症的功能。This study was aimed to observe the effect of gold buckwheat fermented tea on both acute and chronic inflammation in mice. Ear swelling was induced by xylene. Toe swelling was induced by carrageenan. The acute inflammation model was induced by the increasing of capillary permeability in the abdomen of mice by acetic acid. The chronic inflammation model of granuloma was used in the evaluation of anti-inflammatory function of gold buckwheat fermented tea. The results showed that the gold buckwheat fermented tea can obviously decrease the rate of xylene-induced ear swelling and the degree of carrageenan-induced toe swelling in mice. And the gold buckwheat fermented tea had antagonism effect on acute inflammation caused by acetic acid through the increasing of capillary permeability in abdomen of mice. Furthermore, the gold buckwheat fermented tea had obvious inhibition effects on proliferation of granuloma in chronic inflammation. It was concluded that the gold buckwheat fermented tea had the prevention and treatment effect on both acute and chronic inflammation.

关 键 词：金荞麦叶发酵茶 抗炎 耳肿胀 足肿胀 腹腔通透性 棉球肉芽肿 

分 类 号：R285.5[医药卫生—中药学]