二氧化碳应用于结肠息肉高频电凝电切术的临床效果  

Clinical effects of application of carbon dioxide in highfrequency electrocoagulation resection of colonic polyps

作　　者：王颖[1] 苏连明[1] 刘丽[1] 宋彬彬[1] 陈爱东[1] 

机构地区：[1]黑龙江省牡丹江医学院红旗医院消化内科,黑龙江省牡丹江市157011

出　　处：《世界华人消化杂志》2015年第22期3634-3637,共4页World Chinese Journal of Digestology

基　　金：牡丹江市科学技术计划基金资助项目;No.z2014s013~~

摘　　要：目的:本实验以空气为对照,结肠息肉高频电凝电切术时注入CO2,观察其安全性与有效性.方法:将140例接受肠息肉治疗患者随机分成CO2组(70例)和空气组(70例),息肉切除时分别注入CO2和空气,记录每组患者肠镜检查前、检查过程中及检查后的动脉血CO2分压,采用直观模拟评分(visual analog score,VA S)量表对结肠镜检查检查后1、3、6和24 h腹胀腹痛严重程度进行评分并记录,记录两组患者完成时间及24 h后满意度,组间比较采用t检验,计数资料用?2检验进行统计学分析.结果:两组患者均顺利完成息肉电切术,CO2组血CO2分压检查前(38.91 mm Hg±5.02mm Hg)、检查中(40.54 mm Hg±4.82 mm Hg)及检查后(39.46 mm Hg±5.15 mm Hg)与空气组血CO2分压检查前(38.52 mm Hg±4.40mm Hg)、检查中(38.87 mm Hg±4.58 mm Hg)及检查后(38.74 mm Hg±4.21 mm Hg)对比无统计学差异(P>0.05);而检查中、后1、3和6 h的CO2组患者腹胀腹痛程度平均VAS分值均明显低于空气组(P<0.05).两组患者完成时间无统计学差异(P>0.05);CO2组患者24 h后满意度调查明显优于空气组.结论:结肠息肉高频电凝电切术中注入CO2可明显减轻患者术中术后腹痛腹胀,不会引起CO2潴留,不影响治疗时间,提高患者满意度,值得临床推广使用.AIM：To evaluation the efficacy and safety of application of carbon dioxide（CO2） in highfrequency electrocoagulation of colonic polyps.METHODS：One hundred and forty patients who received treatment for intestinal polyps at our hospital were randomly divided into an CO2 group（n = 70） and an air group（n =70）.The patients in the two groups received CO2 and air injection upon polyp resection,respectively.The arterial partial pressure of CO2 was recorded before,during and after enteroscopy.The visual analogue score（VAS） scale was used to assess the severity of abdominal distension and pain at 1,3,6 and 24 h after colonoscopy examination.The time of procedure and the rate of patient satisfaction at 24 h were also compared.RESULTS：Electro coagulation of colonic polyps was successful in all patients in the two groups.There was no significant difference in the arterial partial pressure of CO2 before,during or after enteroscopy between the CO2group and air group（38.91 mmHg ± 5.02 mmHg vs 38.52 mmHg ± 4.40 mmHg,40.54 mmHg ± 4.82 mmHg vs 38.87 mmHg ± 4.58 mmHg,39.46 mmHg ± 5.15 mmHg vs 38.74 mmHg ± 4.21 mmHg）（P 〉 0.05）.The average VAS scores at 1,3 and 6 h were significantly lower in the CO2 group than in the air group（P〈 0.05）.There was no significant difference in the time of procedure between the two groups（P 〉 0.05）.The rate of patient satisfaction at 24 h was significantly higher in the CO2 group.CONCLUSION：High-frequency electrocoagulation of colonic polyps with CO2 injection can obviously relieve postoperative abdominal pain and distension and improve the satisfaction of patients.

关 键 词：二氧化碳 结肠息肉 高频电凝电切术 临床研究 

分 类 号：R656[医药卫生—外科学]