山东省寿光市乙型肝炎、乙型肝炎相关肝硬化及肝癌流行趋势分析  

Epidemiological trend of hepatitis B, hepatitis B related liver cirrhosis and liver cancer in Shouguang, Shandong Provinc

作　　者：王晓琼[1] 张国庆[1] 刘中芹 王颖[1] 刘召红[1] 崔佳[1] 

机构地区：[1]山东省寿光市疾病预防控制中心,山东寿光262700

出　　处：《疾病预防控制通报》2015年第4期46-48,94,共4页Bulletin of Disease Control & Prevention(China)

摘　　要：目的分析2008—2013年山东省寿光市乙型肝炎、乙型肝炎相关肝硬化和肝癌的发病趋势,为乙型肝炎防治提供科学依据。方法根据历年报告的乙型肝炎、肝硬化和肝癌发病资料和人口资料,统计分析2008—2013年全市上述3种疾病的发病情况。结果 2008—2013年寿光市共报告乙型肝炎患者1 898人,年平均发病率为29.91/10万,各年龄组之间(χ2=534.04)、各镇(街道)之间(χ2=220.11)发病率差异有统计学意义(均P<0.01),男性(χ2=378.77)、非农业人口(χ2=300.60)、第二季度(χ2=17.77)的发病率显著高于女性、农业人口及其他季节(均P<0.01);乙型肝炎相关原发性肝癌、肝硬化患者1 157人次,共计患者788人,男性发病率明显高于女性(χ2=226.85,P<0.01),发病率随年龄增加而增长(r=0.97,P<0.01)。结论寿光市乙型肝炎发病表现出地区差异、职业差异、性别差异和年龄差异,并且随着年龄增大和病程进展,越来越多的乙型肝炎患者转变成为肝硬化或肝癌患者。Objective To analyze epidemiological trend of hepatitis B, hepatitis B related liver cirrhosis and liver cancer in Shouguang, Shandong during 2008--2013 in order to provide scientific basis for future work of hepatitis B prevention and control. Methods Based on the routine incidence data of hepatitis B, liver cirrhosis, liver cancer and demographic data dur- ing 2008--2013 in Shouguang, the incidence rate were calculated and analyzed. Results Totally 1 898 patients with hepati- tis B were reported during 2008--2013 in Shouguang, with the average incidence rate of 29.91/100 000 per year. There were statistical differences （P〈0.01） among different age groups （Z2=534.04） and townships （Z2=220.11）. There was a significantly higher incidence rate separately in the male （Z2=378.77）, nonagricultural population （Z2=300.60） and the second quarter （Z2= 17.77） than in the female, agricultural population and the other quarters （P〈0.01）. Seven hundred and eighty-eight patients with hepatitis B related liver cirrhosis and liver cancer were reported 1 157 times. The incidence rate was significantly higher in the male than in the female （Z2=226.85, P〈0.01 ） and increased with age （r=0.97, P〈0.01）. Conclusions The incidence of hepatitis B exhibits regional difference, occupational differences, sex difference and age differences, and more and more hepatitis B patients develop to liver cirrhosis or liver cancer patients as age growth and disease progression.

关 键 词：乙型肝炎 肝癌 肝硬化 发病率 

分 类 号：R512.62[医药卫生—内科学]