糖尿病、IGT、IFG及血糖正常人OGTT结果分析  

Analysis of OGTT results in diabetes mellitus, IGT, IFG and normal people

作　　者：张智军 方利伟 

机构地区：[1]洛阳石化医院内分泌科,471012 [2]洛阳市吉利区医院内科

出　　处：《中国实用医药》2015年第22期4-6,共3页China Practical Medicine

摘　　要：目的分析糖尿病、糖耐量低减(IGT)、空腹葡萄糖受损(IFG)及血糖正常人口服葡萄糖耐量试验(OGTT)的结果 ,探讨血糖、胰岛素、C肽变化规律。方法在本院门诊做OGTT的1146人作为研究对象,分为体质量指数(BMI)<24 kg/m2和BMI≥24 kg/m2两种情况下OGTT中各时相的血糖、胰岛素、C肽数值并进行分析。结果糖尿病、IGT、IFG及血糖正常人行OGTT,糖负荷后血糖、胰岛素、C肽峰值出现时间不同,从血糖正常到IFG、IGT、糖尿病的过程中,胰岛素、C肽峰值逐渐后移,峰值延迟。结论从OGTT中可以反映出糖尿病、IGT、IFG及血糖正常人血糖、胰岛素、C肽的变化规律,OGTT不仅是诊断糖尿病的金标准,也是判断胰岛细胞功能的有效方法。Objective To analyze oral glucose tolerance test（OGTT） results in diabetes mellitus, impaired glucose tolerance（IGT）, impaired fasting glucose（IFG） and normal people, and to investigate changing patterns of blood glucose, insulin and C-peptide. Methods A total of 1146 patients receiving OGTT as study subjects were divided into body mass index（BMI） 〈24 kg/m2 and BMI ≥ 24 kg/m2. Blood glucose, insulin and C-peptide were detected in each time phases during OGTT for statistical analysis. Results OGTT in diabetes mellitus, IGT, IFG and normal people showed different occarrence time of blood glucose, insulin and C-peptide peaks. Insulin and C-peptide peaks delayed gradually from normal people, IFG, IGT, to diabetes mellitus. Conclusion OGTT can reveal the changing patterns of blood glucose, insulin and C-peptide in diabetes mellitus, IGT, IFG and normal people. OGTT is the golden standard for diagnosis of diabetes mellitus, as well as an effective method for judging islet cell function.

关 键 词：口服葡萄糖耐量试验 血糖 胰岛素 C肽 

分 类 号：R587.1[医药卫生—内分泌]