介入性产前诊断适应证和禁忌证及应用  

Invasive prenatal diagnosis: indications and application

作　　者：高劲松[1] 刘俊涛[1] 

机构地区：[1]中国医学科学院北京协和医学院北京协和医院妇产科,北京100730

出　　处：《中国实用妇科与产科杂志》2015年第9期825-828,共4页Chinese Journal of Practical Gynecology and Obstetrics

摘　　要：介入性产前诊断是指通过有创的穿刺技术获取胎儿成分(主要包括羊水、脐带血、胎儿组织或胎盘组织),其主要目的是对胎儿进行染色体核型分析,也可用于遗传病的基因检测,以达到在宫内诊断胎儿先天性疾病的目的。介入性产前诊断技术是产前诊断工作实施中的重要环节,其技术主要包括:羊膜腔穿刺、绒毛活检、脐静脉穿刺。各种技术各有特点,互为补充,为开展胎儿先天性疾病的产前诊断提供重要途径。介入性产前诊断为有创性操作,需要权衡穿刺的指征和风险,获得患者的知情同意,并需要一定的技术和条件。Invasive prenatal testing is the way to get fetal cells or placenta tissues in order to make prenatal diagnosis of fetal aneuploidy or other genetics disorders. The most commonly used techniques include amnio- centesis, chorionic villus sampling and fetal blood sampling.These techniques will be used during dif- ferent gestational stage with same or different indica- tions.As these techniques are invasive, they should only be performed with sufficient indications with informed consent of the patient through balancing the benefit and risk of the procedure.Sufficient techniques and con- ditions are also required to conduct prenatal＇ diagnosis.

关 键 词：介入性产前诊断 羊膜腔穿刺 绒毛活检 脐静脉穿刺 

分 类 号：R714.53[医药卫生—妇产科学]