以FPGA为核心的流式细胞仪控制系统设计  

Design of flow cytometry control system based on FPGA

作　　者：吴云良[1] 裴智果[1] 陈忠祥[1] 严心涛[1] 武晓东[1] 

机构地区：[1]中国科学院苏州生物医学工程技术研究所,苏州215163

出　　处：《电子测量技术》2015年第7期58-61,共4页Electronic Measurement Technology

摘　　要：设计了一种以FPGA为核心的流式细胞仪控制系统。利用FPGA高速度、多接口和丰富的逻辑资源等优势,原本庞大复杂,可能拥有几十个电路板,上百甚至上千个芯片的流式细胞仪控制系统,被一个只有十几个芯片的简单电路板取代。这些改进增加了整个系统的可靠性,使其工作速度可以提升到百兆赫兹。很多在原有流式细胞仪控制系统中很难解决的问题,比如多通道数据同步、寻峰、积分等,在FPGA算法中被简单实现。这套系统实现了8路A/D数据同步采集,16路D/A输出,若干数字I/O输出,在实验中稳定实现了流式细胞仪的各种控制操作,并采集了校准小球测试数据,8峰可以明显区分。A flow cytometer control system using FPGA is designed.The traditional flow cytometry control system is very large and complex,with dozens circuit boards,hundreds or even thousands of chips.With the advantages of FPGA＇s high speed,multi-SelectIO interface and abundant logic resources,the control system can be optimized to a simple circuit board,with no more than a dozen chips.The improvements increase the reliability of the whole system,up the system process speed to megahertz.In FPGA algorithm,many difficulty problems are solved easily,such as multi-channel data synchronization,peak search,area integration,etc.The control system can achieve up to 8channels A/D data synchronous acquisition,16 channel D/A output,several digital I/O output.In the experiment,a variety of control operations are steady achieved,and the 8-peak rainbow calibration particles is measured and displayed.

关 键 词：FPGA 流式细胞仪 控制系统 

分 类 号：TP274[自动化与计算机技术—检测技术与自动化装置]