持续声门下吸引术在预防呼吸机相关性肺炎中的效果研究  

Research on the Subglottic Aspiration in the Prevention of Ventilator Associated Pneumonia

作　　者：朱文峰[1] 徐亮[1] 任斌[1] 刘潮勇[1] 朱李兵[1] 潘灵辉 

机构地区：[1]解放军第171医院,江西九江332000 [2]广西肿瘤防治研究所,广西南宁530027

出　　处：《现代生物医学进展》2015年第19期3701-3703,共3页Progress in Modern Biomedicine

基　　金：国家科学基金地区项目(81060008)

摘　　要：目的:探究持续声门下吸引术在预防呼吸机相关性肺炎中的临床效果。方法:选取我院入住重症监护病房并需要机械通气的患者46例,随机分为两组,每组23例。实验组患者予以持续性负压吸引装置,对照组患者不添加负压吸引装置。观察两组患者在机械通气过程中呼吸机相关性肺炎的发生率,以及气道滞留物的菌落培养情况。结果:实验组患者机械通气时间、重症监护住院时间均短于对照组,差异有统计学意义(P<0.05);实验组呼吸机相关性肺炎发病率低于对照组,差异有统计学意义(P<0.05);实验组大肠杆菌、非发酵菌、革兰阳性球菌的发现率均低于对照组,差异有统计学意义(P<0.05)。结论:持续声门下吸引术能够减少患者机械通气的时间,降低呼吸机相关性肺炎的发病率,提高安全性,值得临床推广。Objective： To explore the clinical effect of subglottic aspiration in prevention of ventilator associated pneumonia. Methods： 46 cases admitted to the intensive care unit and require mechanical ventilation from our hospital were randomly divided into two groups, each group of 23 patients. 23 cases in experimental group were treated immediately with continuous negative pressure suction device, while the control group without it. Then the incidence of ventilator associated pneumonia, and airway retentate colony culture situation were observed and compared between the two groups. Results： The time of mechanical ventilation and hospitalization of the patients in the experimental group were much shorter than those of the patients in the control group with statistically significant differences （P〈0.05）; the incidence of the ventilator associated pneumonia in the experimental group was lower than that of the control group with statistically significant differences（P〈0.05）; the incidence of the enterobacteriaceae colonies, the fermentation bacteria colony, and the gram positive coccus in the experimental group were significantly lower than those of the control group, and the differences were statistically significant between two groups （P〈0.05）. Conclusions： Subglottic aspiration continuously can reduce the time of mechanical ventilation and the hospitalization, as well as improve the retention of upper respiratory tract, that could reduce the incidence of ventilator associated pneumonia and improve the clinical efficacy.

关 键 词：呼吸机相关性肺炎 机械通气 持续声门下吸引术 

分 类 号：R563.1[医药卫生—呼吸系统]