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作 者:顾峥嵘[1,2] 王海鹏[1,2] 颜家骅[1,2] 刘云吉[1,2] 徐菁[1,2] 郑鸿[3] 陈学明
机构地区:[1]上海市静安区中心医院 [2]复旦大学附属华山医院静安分院骨科,上海200401 [3]广东医学院附属医院骨科,广东湛江524200 [4]湖南株洲市三三一医院,湖南株洲412002
出 处:《现代生物医学进展》2015年第21期4124-4127,共4页Progress in Modern Biomedicine
基 金:卫生部科技计划项目(W2012ZT72)
摘 要:摘目的:探讨髋关节骨性关节炎患者生存质量现状及其影响因素。方法:选择60例髋关节骨性关节炎患者作为观察组,60例健康者作为对照组。采用SF-36生存质量评价量表,比较观察组与对照组SF-36量表各维度评分;分析影响患者生存质量的因素。结果:①观察组SF-36量表各维度评分均显著低于健康对照组,差异均具有统计学意义(P〈0.05);②经Pearson单因素分析,SF-36量表综合得分在性别、职业、痛程、治疗前景、内科慢性疾病数、10m步行速度及K-L分级方面的差异均具有统计学意义(P〈0.05-4).01);⑨经多元Logistic回归分析,病程(β=0.772,S.E.=0.689,Wald=34.027,P〈0.05,OR=1.99)、治疗前景(B=0.778,S.E.=0.542,Wald=55.638,P〈0.05,OR=1.88)、内科慢性疾病数(B=0.929,S.E.=0.301,Wald=12.382,P〈0.05,OR=I.72)、10m步行速度(p=0.661,S.E.=0.381,Wald=19.929,P〈0.05,OR=I.69)及K-L分级(β=0.992,S.E.=0.526,Wald-28.371,P〈0.05,OR=2.31)为影响髋关节骨性关节炎患者生存质量的危险因素。结论:髋关节骨性关节炎患者生存质量明显差于健康者,病程、治疗前景、内科慢性疾病数、10m步行速度及K-L分级是影响患者生存质量的危险因素。Objective: To investigate the factors of hip osteoarthritis patients survival quality and its influence. Methods: 60 cases of hip osteoarthritis patients as the observation group, and 60 healthy persons who had physical examination in our hospital during the same period as the control group. Apply the SF-36 quality of life scale to compare scores of dimensions between observation group and control group, and analyze the factors influencing the quality of life of patients with confirmed hip osteoarthritis. Results: ① Patients in observation group had lower scores of each dimension than that those in control group, and the difference was statistically significant (P〈0.05); ② Through the Pearson single factor analysis, the comprehensive scores of SF-36 scale had statistically significant difference in gender, occupation, course of disease, therapeutic prospect, internal chronic diseases, 10 m walking speed and K-L classification between two groups (P 〈 0.05~0.01); ③By multivariate Logistic regression analysis, the risk factors affecting the life quality of hip osteoarthritis patients included the course of the disease (β=0.772, S.E.=0.689, Wald=34.027, P 〈 0.05, OR=1.99), the prospects for cure (β=0.778, S. E.=0.542, Wald=55.638, P 〈 0.05, OR=1.88), the number of chronic diseases in Department of internal medicine (β=0.929, S.E.=0.301, Wald=12.382, P〈0.05, OR =1.72), 10 m walking speed (β=0.661, S.E.=0.381, Wald=19.929, P〈0.05, OR=1.69) and K-L classifica- tion (β=0.992, S.E.=0.526, Wald=28.371, P〈0.05, OR=2.31). Conclusion: The hip osteoarthritis patients had obviously poorer life quality than healthy persons. Risk factors like course of disease, therapeutic prospect, internal chronic diseases, 10 m walking speed and K-L classification greatly affected the quality of life of hip osteoarthritis patients.
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