利用功能性近红外光谱法研究大脑皮层血氧情况随任务特征变化规律  

Study on Variation in Cortex Oxygen with Task Features Using Functional Near-Infrared Spectroscopy

作　　者：潘津津[1] 焦学军[1] 焦典[2] 王春慧[1] 徐凤刚[1] 姜劲[1] 张朕[1] 曹勇[1] 

机构地区：[1]中国航天员科研训练中心人因工程国家重点实验室,北京100094 [2]天津大学精密仪器与光电子工程学院,天津300192

出　　处：《光学学报》2015年第8期226-232,共7页Acta Optica Sinica

基　　金：国家973计划(2011CB711000);国防重点实验室自主课题(HF2011-Z-Z-A-01);飞天基金(FTKY201509)

摘　　要：功能性近红外光谱(f NIRS)成像是一种新兴的光学脑成像技术。已有大量基于f NIRS简单任务脑力负荷评估方面的研究,但当实验任务从单一简单任务变化为复杂综合任务时,相应方法不能直接简单套用。借助于f NIRS技术,通过复杂任务特征分解的思路进行尝试,研究大脑皮层血氧情况随复杂任务各任务特征的变化规律,为f NIRS评估复杂任务脑力负荷等研究提供思路和基础。结果发现:前额叶大脑皮层(PFC)区域的含氧血红蛋白(Hb O)对复杂度、时间压力和有无控制三种任务特征的变化均有较高的激活程度响应;视觉皮层(VC)区域的Hb O对不同时间压力任务特征导致的任务难度变化有较高的激活程度响应,但对不同复杂度和有无控制特征的激活程度响应较低;运动皮层(MC)区域Hb O对有无控制输出特征有较高的激活程度响应,对不同时间压力特征的激活程度响应较弱。Functional near-infrared spectroscopic （fNIRS） imaging is an emerging optical brain imaging technique. Numerous studies have been carried out for assessment of mental workload in simple tasks by fNIRS, but these methods can not be directly applied when the experimental task is complex and integrated. A task decomposition idea is tried to study the variation in cortex blood oxygen with every task feature of complex task using fNIRS, and to find ideas and basis for mental workload assessment in complex tasks. The results show that the activation degree of oxygenated hemoglobin （HbO） in prefrontal cortex （PFC） area makes response to the change of complexity, time pressure, and with or without control strongly; the area of visual cortex （VC） has strong activation degree as the feature of time pressure changes, but weak activation for complexity and with or without control; motor cortex （MC） has strong activation degree with the feature of control existing or not, but its relationship with the change of complexity and time pressure is weak.

关 键 词：医用光学 功能性近红外光谱成像 血氧变化 含氧血红蛋白 激活程度 

分 类 号：O433.4[机械工程—光学工程] TP274.52[理学—光学]