血糖波动系数及CRP水平对危重症患者预后的评估价值  

The prognostic value of glucose variability and CRP in critically ill patients

作　　者：蒋建红[1] 王勇[1] 刘文明[1] 谈铁武 孟丽君[1] 霍中雷 汤艳[1] 陈琦[1] 

机构地区：[1]南京医科大学附属常州市第二人民医院重症医学科,江苏常州213003

出　　处：《临床急诊杂志》2015年第8期607-609,共3页Journal of Clinical Emergency

基　　金：常州市科技计划项目(No:WZ201021)

摘　　要：目的:观察危重症患者血糖波动系数(GV)及炎性因子C反应蛋白(CRP)的水平,并评估其在判断预后中的价值。方法:搜集71例危重症患者入院24h内的血糖监测值及CRP水平,计算GV与CRP水平的相关性,并分析GV与危重症患者APACHEⅡ评分的关系,追踪其早期预后。结果:全部患者入院时血清CRP水平均较正常值高,且GV与CRP呈正相关(P<0.01);GV、CRP与APACHEⅡ评分均呈正相关(均P<0.01);低GV组预后明显优于高GV组(P<0.05)。结论:危重症患者GV与血清CRP均明显升高且二者间存在正相关关系,GV可作为预测危重症患者预后的独立因素,故临床治疗过程中应通过积极控制血糖波动水平改善预后。Objective：To detect the glucose variability and CRP in critically ill patients,and evaluate prognostic value and the relationship between them.Method：We retrospectively analyzed 71 critically ill patients,the GV and CRP were recorded.Relationship between the GV and CRP,and the correlation between GV and APACHE Ⅱscore were analyzed.High and low GV groups were compared to predict prognosis.Result：Both the GV and CRP were higher and abnormal,and the positive correlations were found between them（P〈0.01）.There were positive correlation of GV and CRP with APACHEⅡ Score（P〈0.01）;The prognosis was better in lower-GV group than in high GV group.Conclusion：In critically ill patients,GV and CRP were higher,and the positive correlations were found between them.GV was significantly associated with the severity of disease and prognosis.So it＇s important to control the glucose variability to improve the prognosis.

关 键 词：血糖波动系数 C反应蛋白 危重症 

分 类 号：R459.7[医药卫生—急诊医学]