心肺脑复苏过程中亚低温治疗的研究进展  

Progress in the study of brain injury treatment with successful resuscitation after cardiac arrest with mild hypothermia therapy

作　　者：李玉生[1] 聂时南[1] 

机构地区：[1]南京军区南京总医院急救医学科,南京210002

出　　处：《临床急诊杂志》2015年第8期648-652,共5页Journal of Clinical Emergency

基　　金：中国人民解放军全军后勤面上项目(No:CNJ14L002);南京军区面上项目(No:14ms111)

摘　　要：根据2010年美国心脏协会（American Heart Association,AHA）公布的心肺脑复苏（CPCR）与心血管急救（ECC）指南,脑复苏是CPCR的主要目的〔1〕。在欧美等发达国家,院外心脏骤停的年发生率约为1/1 500,这意味着仅在欧洲每年就有大约375 000人发生心脏骤停。最近的一项系统性分析表明心脏骤停患者生存率仅6.7%-8.4%,并且仅有1.4%的患者能够达到脑功能的完全恢复〔2〕。Recently the mild hypothermia therapy is widely used in treatment of brain injury with successful resuscitation after cardiac arrest,and the good clinical effects have obtained.But,in recent years,how to improve the function of patients with cardiopulmonary resuscitation recovery has become a research hotspot.Therefore,we summarized the concept of mild hypothermia therapy,the mechanisms of brain injury after cardiac arrest,the cerebral protective mechanisms of mild hypothermia therapy,the implementation strategy of mild hypothermia therapy,the side effects and the management of mild hypothermia therapy and the prospect of mild hypothermia therapy.

关 键 词：亚低温 心脏骤停 复苏 脑损伤 

分 类 号：R459.7[医药卫生—急诊医学]