注射用牛肺表面活性剂治疗足月剖宫产儿呼吸窘迫综合征的临床观察及护理  

Clinical observation and nursing care of calf pulmonary surfactant for injection on respiratory distress syndrome in full term infant of cesarean section

作　　者：李玉兰[1] 

机构地区：[1]山东省日照市人民医院护理部,276826

出　　处：《中国实用护理杂志》2015年第19期1444-1447,共4页Chinese Journal of Practical Nursing

摘　　要：目的 评价注射用牛肺表面活性剂治疗足月剖宫产儿呼吸窘迫综合征（RDS）的临床疗效及安全护理措施.方法 将30例足月剖宫产RDS患儿按患儿家属意愿分为2组,A组17例,给予气管内滴入注射用牛肺表面活性剂后,据病情需要给予呼吸机治疗,B组13例,除不使用注射用牛肺表面活性剂外,其余治疗2组患儿相同.比较2组患儿治疗前后的血气分析变化、机械通气时间、X线双肺恢复时间、住院时间等.结果 治疗后A组动脉血氧分压为（75.6±16.2） mmHg（1 mmHg=0.133kPa）,B组动脉血氧分压为（54.8±12.4） mmHg,2组比较差异有统计学意义,t=3.84,P＜0.01.A组治愈率16/17,相关性肺损伤发生率1/17,需供氧时间（3.2±1.4）d,住院时间（7.2±1.8）d,B组上述指标分别为7/13、6/13,（5.6±2.1）d、（14.7±2.4）d,2组比较差异有统计学意义,P＜0.05或＜0.01.结论 使用注射用牛肺表面活性剂治疗足月剖宫产儿RDS安全有效,精心护理是关键.Objective To evaluate the efficacy and safety of calf pulmonary surfactant for injection on respiratory distress syndrome （RDS） in full term infant of cesarean section.Methods A total of 30 RDS in full term infant of cesarean section were divided into 2 groups according to family members intend.A group with 17 cases was given endotracheal drip into the calf pulmonary surfactant for injection and breath machine treatment according to the illness needs.B group with 13 cases was given the same treatment with A group except for calf pulmonary surfactant for injection.The changes of blood gas analysis before and after treatment,mechanical ventilation time,X-ray recovery time and hospital stays were compared between 2 groups.Results Arterial blood oxygen partial pressure after treatment in A,B group were （75.6±16.2）,（54.8±12.4） mmHg （1 mmHg=0.133 kPa）,and there was significant difference between 2 groups,t=3.84,P〈0.01.The incidence of cure,ventilation related lung injury and oxygen time needs,hospital stays were 16/17,1/17,（3.2±1.4） d,（7.2±1.8） d in A group,and 7/13,6/13,（5.6±2.1） d,（14.7±2.4） d in B group,and there were significant differences,P〈0.05 or 〈0.01.Conclusion Calf pulmonary surfactant for injection in treatment of RDS in full term infant of cesarean section,which is safe and effective and is worthy of promotion.

关 键 词：剖宫产术 呼吸窘迫综合征 新生儿 护理 足月儿 

分 类 号：R473.72[医药卫生—护理学]