红外激光脉冲加热下耳蜗内温度变化的模拟研究  

Modeling of laser heating in cochlea stimulated by infrared pulse-trains

作　　者：张开银[1] 杨群[1] 武山[1] 赵书涛[1] 吴言宁[1] 刘广东[1] 王秋玲[1] 

机构地区：[1]阜阳师范学院物理与电子工程学院,安徽阜阳236037

出　　处：《阜阳师范学院学报（自然科学版）》2015年第3期25-28,共4页Journal of Fuyang Normal University(Natural Science)

基　　金：安徽省自然基金(1308085MA13);教育部留学回国科研启动金(2012-42);安徽省高等学校省级自然科学研究项目(KJ2012Z307);安徽省大学生创新训练项目(AH201410371034);阜阳师范学院质量工程项目(2014JXTD01)资助

摘　　要：建立了一个三维光热模型,应用该模型分别研究了红外激光脉冲在人耳蜗和动物耳蜗内由于激光吸收引起的温度变化。采用有限元方法,数值模拟了耳蜗内温度在空间和时域的变化。研究发现尽管激光吸收引起了一定的温度升高,但是可以通过调节激光脉冲参数比如激光功率和重复频率对温度变化进行控制。通过对比相同参数的激光脉冲在豚鼠耳蜗内和人耳蜗内引起的温度变化,发现动物耳蜗内温度升高较明显。因此从激光热效应的角度看,动物实验能有效帮助合理选择激光在人耳蜗内的安全参数。A simplified 3D model has been developed to simulate heating effects in human cochlea and guinea pig cochlea when infrared laser pulses are applied to stimulate their ganglion neurons. It simplifies the spiral structure of the cochlea by a rota- tional symmetry with the 3D structure of the cochlea, and applies the finite element method to solve the heat equation and allows de- tailed investigation of the temperature rise in spatial and temporal domains. The numerical results show that the temperature rises within cochleae can he controlled in a safe range by adjusting the laser power and repetition rate. Additionally, the results show that the heating in guinea pig cochlea is higher than that in human eoeldea because of the effect of the boundary conditions. It indicates that experiments with laser safety performed on guinea pig cochlea could be a good guidance for studying laser safety in human.

关 键 词：耳蜗 红外激光脉冲 光热 温度升高 

分 类 号：R764.35[医药卫生—耳鼻咽喉科]