铂纳米粒子自组装膜电极差分脉冲伏安法测定多巴胺  

Platinum nanoparticles / ethanedithiol modified gold electrode differential pulse voltammetry for the determination of dopamine

作　　者：张雷[1] 孙邦锦 董书顶 刘玉婷[1] 魏敏[1] 李芬培 张宏[1] 

机构地区：[1]阜阳师范学院化学与材料工程学院,安徽阜阳236037

出　　处：《阜阳师范学院学报（自然科学版）》2015年第3期39-43,共5页Journal of Fuyang Normal University(Natural Science)

基　　金：安徽省高校自然科学基金项目(KJ2011A210);大学生创新创业训练计划项目(AH201410371001);安徽省本科教学工程项目(2014sjjd018;2014JXTD03;2013zytz042;2012ZYSD01;20100633;2011JPKC03)资助

摘　　要：本文选用1,2-乙二硫醇为连接剂,通过共价键将PVP保护的铂纳米粒子（Pt NPs）固定在金电极表面,制成铂纳米粒子/乙二硫醇修饰的金电极。在PH=7.0的环境下,利用差分脉冲伏安法（DPV）测定多巴胺（DA）。结果表明,在1.0×10-5~1.0×10-3mol/L范围内,峰电流与多巴胺浓度成线性关系,检测限为5.0×10-6mol/L。实验同时考察了抗坏血酸（AA）对测定结果的影响,结果显示在DA和AA混合液的DPV曲线上出现两个峰,故修饰电极能够在AA共存下选择性测定DA。In this topic 1,2-ethanedithiol was employed as a linker to fix platinum nanopartieles protected by PVP on the sur- face of gold electrode through covalent bond to construct the platinum nanoparticles/ethanedithiol modified gold electrode （ PtNPs/ EDT/Au）. This modified electrode was used to detect dopamine （DA） by differential pulse voltammetry （DPV）. The peak currents are linear with concentration of DA in the range of 1.0×10-5~1.0×10-3mol/L with the detection limit as 5.0×10-6 mol/L. Mean- while, the effect of ascorbie acid （AA） on the detection of DA was studied, and the result showed that two separated peak of DA and AA can be observed in DPV curve, which indicated the PtNPs/EDT/Au can be used to detect dopamine in the presence of AA.

关 键 词：多巴胺 铂纳米粒子 1 2-乙二硫醇 差分脉冲伏安法 

分 类 号：O657.1[理学—分析化学]