综合干预措施可降低重症监护病房多重耐药菌医院感染发病率  

Comprehensive intervention measures can reduce incidences of multidrugresistant organism healthcare-associated infection in intensive care units

作　　者：刘彩红[1] 李福琴[1] 刘盛楠[1] 王秋亚[1] 李俊艳[1] 吴安华[2] 文建国[1] 

机构地区：[1]郑州大学第一附属医院,河南郑州450052 [2]中南大学湘雅医院,湖南长沙410008

出　　处：《中国感染控制杂志》2015年第8期553-556,共4页Chinese Journal of Infection Control

基　　金：中国医院协会医院感染预防与控制能力建设项目(CHA-2012-XSPX-0629-1)

摘　　要：目的探讨综合干预措施对降低重症监护病房（ICU）多重耐药菌（MDRO）医院感染发病率的作用。方法 选取某院6个成人ICU2014年1—12月收治的重症患者,2014年1—6月入院的患者作为对照组（不采取特殊干预措施）,2014年7—12月入院的患者作为综合干预组（采取MDRO防控综合干预措施）,比较两组患者MDRO医院感染发病率。结果 综合干预组收治的1 030例患者中,391例检出MDRO,发生MDRO医院感染105例,医院感染日发病率为7.63‰（105/13 753）;对照组收治的1 230例患者中,596例检出MDRO,发生MDRO医院感染133例,医院感染日发病率为27.12‰（133/4 905）,综合干预组医院感染日发病率低于对照组,差异有统计学意义[RR及95%CI为0.28（0.22-0.37）,P〈0.001]。结论 综合干预措施可有效降低ICU MDRO医院感染发病率。Objective To evaluate the effectiveness of comprehensive intervention measures in reducing the incidences of multidrug-resistant organism（MDRO）healthcare-associated infection（HAI）in intensive care units（ICUs）.Methods Patients admitted to 6 adult ICUs between January and December 2014 were chosen,and divided into two groups,patients admitted to ICUs between January and June 2014（without taking special intervention measures）were as control group,between July and December 2014（taking comprehensive MORO prevention and control measures）were as comprehensive intervention group.Incidences of MDRO HAI of two groups were compared.Results Of 1 030 patients in comprehensive intervention group,391 were detected MDROs,105 developed MORO HAI,incidence of HAI was 7.63/1 000 patient-days（105/13 753）;of 1 230 patients in control group,596 were detected MDROs,133 developed MORO HAI,incidence of HAI was 27.12/1 000 patient-days（133/4 905）,incidence of HAI in comprehensive intervention group was significantly lower than control group（RR,0.28[95%CI,0.22-0.37],P〈0.001）.Conclusion Comprehensive intervention measures can effectively reduce the incidence of MORO HAI in ICUs.

关 键 词：多重耐药菌 综合干预措施 医院感染 发病率 

分 类 号：R181.32[医药卫生—流行病学]