两种注射速度对钆塞酸二钠磁共振肝脏动态增强动脉期图像质量的影响  

Influence of injection speed on quality of arterial phase images of liver in Gd-EOBDTPA-enhanced MR imaging

作　　者：赵骏[1] 黎川[1] 陈伟[1] 张琳[1] 王健[1] 周代全[1] 

机构地区：[1]第三军医大学西南医院放射科,重庆400038

出　　处：《第三军医大学学报》2015年第17期1792-1796,共5页Journal of Third Military Medical University

摘　　要：目的比较两种注射速度(1、1.5 m L/s)钆塞酸二钠(Gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid,Gd-EOB-DTPA)增强磁共振(magnetic resonance,MR)肝脏动态增强动脉期图像质量的优劣性。方法回顾性评估本院2012年12月至2013年9月接受Gd-EOB-DTPA肝脏MR动态增强检查的患者106例,包括注射速度为1 m L/s患者52例,1.5 m L/s患者54例,对动脉期增强图像进行评估。由2名副高以上诊断医师定量评估所有患者肝脏动脉期腹主动脉、肝总动脉、肝脏实质的信噪比(signal noise ratio,SNR)和强化率(contrast-enhancement ratio,CER)的差异性,定性评估腹主动脉、肝总动脉、肝脏实质、门静脉和图像伪影5个项目得分和总分的差异性。结果 Gd-EOB-DTPA注射速度为1 m L/s组和1.5 m L/s组各部分SNR和CER差异无统计学意义(P>0.05),1 m L/s组腹主动脉、肝总动脉强化评分和总分均高于1.5 m L/s组(P<0.05)。结论 Gd-EOB-DTPA注射速度为1 m L/s的肝脏动脉期图像质量优于注射速度为1.5 m L/s的肝脏动脉期图像质量。Objective To explore the influence of 2 different injection speeds on the arterial phase image quality of liver in gadolinium ethoxybenzyl diethylenetriaminepentaacetic acid（ Gd-EOB-DTPA）-enhanced MR imaging. Methods Hepatic arterial phase images were obtained after injecting Gd-EOB-DTPA contrast agent at 2 different injection speeds. Totally,106 patients performed Gd-EOB-DTPA-enhanced MR imaging from December 2012 to September 2013,and 52 patients were treated at the injection speed of 1 m L / s while 54 patients were treated at the injection speed of 1. 5 m L / s. Two radiologists quantitatively evaluated the signal-to-noise（ SNR） and contrast-enhancement ratio（ CER） of enhanced liver parenchyma,abdominal aorta and common hepatic artery,and qualitatively evaluated the scores of 5 items including liver parenchyma,abdominal aorta,common hepatic artery,portal vein,image artifact and the total score of all the 5 items in the hepatic arterial phase. Results The SNR and CER of liver parenchyma,abdominal aorta,and common hepatic artery had no significant difference between the 1 m L / s group and the 1. 5 m L / s group（ P 0. 05）.The mean scores of the abdominal aorta and common hepatic artery and the total score of the 5 items in the1 m L / s group were significantly higher than those in the 1. 5 m L / s group（ P 0. 05）. Conclusion Based on the quantitative and qualitative evaluation,the image quality in the hepatic arterial phase is better when the injection speed of Gd-EOB-DTPA is 1 m L / s than that when the injection speed is 1. 5 m L / s.

关 键 词：动脉期 钆塞酸二钠 信噪比 强化率 注射速度 

分 类 号：R445.2[医药卫生—影像医学与核医学] R811.5[医药卫生—诊断学]