浅谈长寿信号通路及它们在不同组织间的传递  

Longevity Signaling Across Tissues

作　　者：沈义栋[1] 

机构地区：[1]中国科学院上海生命科学研究院生物化学与细胞生物学研究所,细胞生物学国家重点实验室,细胞信号网络协同创新中心,上海200031

出　　处：《中国细胞生物学学报》2015年第8期1067-1073,共7页Chinese Journal of Cell Biology

基　　金：上海市浦江人才计划项目(批准号:14PJ1410100)资助的课题~~

摘　　要：衰老受着众多信号通路的调节。对于多细胞生物,这些衰老相关信号不仅在细胞内进行传递,更在细胞组织间进行通讯。该文拟结合几条具体的长寿信号通路,综述长寿信号在跨越组织协调全身衰老进程的机制。Ageing is regulated by multiple signaling pathways. In metazoan, these longevity signals are transduced intracellularly and intercellularly as well. This review is to summarize the mechanisms underlying the transduction of longevity signals across tissues, with the examples of several longevity pathways.

关 键 词：衰老 长寿通路 信号跨组织转导 

分 类 号：Q419[生物学—生理学]