肾上腺Castleman病一例临床分析并文献复习  

Adrenal Castleman′s disease：A case report and literature review

作　　者：王凯[1] 陈瑛[1] 赵红燕[1] 陆洁莉[1] 祝宇[2] 方文强[3] 王卫庆[1] 宁光[1] 

机构地区：[1]上海交通大学医学院附属瑞金医院内分泌代谢病科,上海市内分泌代谢病研究所,上海市内分泌代谢病临床医学中心,200025 [2]上海交通大学医学院附属瑞金医院泌尿外科,200025 [3]上海交通大学医学院附属瑞金医院影像科,200025

出　　处：《中华内分泌代谢杂志》2015年第8期672-677,共6页Chinese Journal of Endocrinology and Metabolism

摘　　要：目的：分析肾上腺Castleman病的临床特征及诊疗方法。方法对本院确诊的1例肾上腺Castleman病的临床和病理特点进行回顾性分析，并复习相关文献，总结该病的临床特点以及病因。结果该患者系体检发现肾上腺意外瘤，总结临床特征如下：（1）发病隐匿，表现为后腹膜巨大占位，伴有后腹膜淋巴结肿大；（2）无肾上腺功能异常；（3）术后病理证实为肾上腺Castleman病，透明血管型；（4）手术切除为首选治疗，局限性肾上腺Castleman病预后好。结论肾上腺Castleman病多以肾上腺区巨大占位为主要临床表现，对该病临床特征的深入了解，临床医师与病理医师的合作有助于临床早期诊断和治疗，避免漏诊或误诊。Objective To raise the awareness of adrenal Castleman′s disease by analyzing the clinical features and management of a patient with adrenal Castleman′s disease. Methods A case of adrenal Castleman′s disease of our hospital was retrospectively analyzed, including clinical feature, laboratory findings, pathology, treatment, and follow-up. All the data and pertinent literatures were reviewed and analyzed. Results An incidentaloma measuring 4. 8 cm ＆#215; 6. 3 cm in the right adrenal gland was observed in a 30-year-old men in a ultrasonography examination performed due to a medical check-up. Laboratory analysis showed that the lesion was not hyperfunctioning. The patient subsequently underwent an exploratory laparotomy. Pathological examination revealed retroperitoneally localized Castleman′s disease of the hyaline vascular type. Conclusion Adrenal Castleman′s disease is a rare cause of lymph node hypertrophy, and it is necessary to keep in mind the possibility of its occurrence and take it into consideration in the differential diagnosis of any solitary, heterogeneous, and hypervascular retroperitoneal mass. The proper cooperation between the clinician and pathologist allows early diagnosis and suitable therapy.

关 键 词：肾上腺Castleman病 临床特征 诊断 病因 

分 类 号：R699.3[医药卫生—泌尿科学]