泌尿系结石化学成分对超声声影强弱的影响  

Effects of chemical composition of urinary stones on their acoustic shadowing

作　　者：刘青[1] 商蒙蒙 孙霄[1] 李杰[1] 杨杰[2] 时丹丹[1] 宁松[1] 

机构地区：[1]山东大学齐鲁医院超声科,山东济南250012 [2]山东省荣军总医院超声科,山东济南250013

出　　处：《山东大学学报（医学版）》2015年第9期19-23,共5页Journal of Shandong University:Health Sciences

基　　金：山东大学基本科研业务专项资金[山东大学齐鲁医院科研基金(2015QLMS39)]

摘　　要：目的 定量研究结石化学成分与超声声影的关系。方法 制备一水草酸钙、羟基磷灰石、胱氨酸和尿酸结石模型,包埋于猪肾中进行超声扫查及CT扫描,记录各结石模型所产生声影的对比噪声比（C/N）及CT值,并行统计分析。结果 所有结石均表现为强回声伴后方声影征象,声影C/N值大小为1.01~3.74,平均为2.17;以结石化学成分分组,超声声影C/N值及CT值由大到小排列依次为羟基磷灰石、一水草酸钙、胱氨酸、尿酸,差异有统计学意义（P均〈0.001）;声影C/N值与CT值呈正相关（r=0.942,P〈0.001）。结论 结石所产生的声影强弱程度与其化学成分密切相关,且声影的强弱趋势与CT值大小趋势一致;可通过声影的强弱程度对结石化学成分进行初步预测。Objective To quantitatively analyze the association between chemical composition of urinary stones and acoustic shadowing. Methods Calcium oxalate monohydrate, hydroxyapatite, cystine, and uric acid stone phantoms were prepared and embedded in porcine kidneys for ultrasound and CT scanning. The contrast-to-noise ratio （C/N） of acoustic shadowing and Hounsfield unit were recorded. All data obtained were analyzed statistically. Results All stones demonstrated nigh acoustic echo with shadowing. Of all stone phantoms, C/N ratio was 1.01-3.74, 2.17 in av- erage. The hydrocyapatite stones displayed the strongest C/N ratio of acoustic shadowing and Hounsfield unit, followed by calcium oxalate monohydrate, cystine and uric acid stones （ all P 〈0.001 ）. The C/N ratio was significantly correla- ted with the Hounsfield unit （ r = 0. 942, P 〈 0.001 ） for all stone phantoms. Contusion Stones with different chemi- cal compositions have different acoustic shadowing, but the clarity of acoustic shadowing has the same trend with the Hounsfield unit, and acoustic shadowing can be used to predict the chemical compositions.

关 键 词：超声 声影 电子计算机断层扫描 泌尿系结石 化学成分 

分 类 号：R816.7[医药卫生—放射医学]