甘精胰岛素联合二甲双胍在2型糖尿病临床治疗中的应用价值  

Clinical Application Value of Insulin Glargine Combine With Metformin in Treatment Type 2 Diabetes

作　　者：谢立凯[1] 齐晨蕊[1] 孙亚东[1] 

机构地区：[1]吉林省人民医院内分泌一科,长春130000

出　　处：《中国继续医学教育》2015年第23期143-144,共2页China Continuing Medical Education

摘　　要：目的 分析甘精胰岛素联合二甲双胍治疗2型糖尿病的临床效果.方法 选取2012年12月-2014年12月我院收治的2型糖尿病患者76例,随机分为对照组和观察组,各38例.对照组采用二甲双胍缓释片治疗,观察组采用甘精胰岛素联合二甲双胍治疗,对比两组临床治疗效果.结果 观察组血糖达标时间、餐后2 h血糖、糖化血红蛋白均低于对照组,P〈0.05,差异具有统计学意义;观察组低血糖发生率低于对照组,P〈0.05,差异具有统计学意义.结论 甘精胰岛素联合二甲双胍治疗2型糖尿病疗效确切,能够控制血糖,减少低血糖反应.Objective To analysis clinical effect of insulin glargine study metformin in type 2 diabetes.Methods Selected 76 cases of type 2 diabetes mellitus patients from December 2012 to December 2014 in our hospital, were randomly divided into the control group and the observation group, each group had 38 cases. The control group treated with metformin zyban, the observation group used insulin glargine with metformin therapy, compared clinical therapeutic effect of two groups.Results The observation group blood glucose control was at that time, 2 hours postprandial blood glucose, glycosylated hemoglobin were less than the control group, P〈0.05, had difference statistically significance, the observation group hypoglycemia rate was lower than the control group,P〈0.05, had difference statistically significance.Conclusion Insulin glargine with metformin therapy in type 2 diabetic curative effect, can control the blood sugar,reduce the hypoglycemia.

关 键 词：二甲双胍 甘精胰岛素 2型糖尿病 疗效 

分 类 号：R587.1[医药卫生—内分泌]