温针灸配合元素钙防治绝经后骨质丢失临床研究  

Warm needling combined with element calcium for postmenopausal osteoporosis

作　　者：蔡国伟[1] 李静[1] 薛远志[1] 李刚[1] 吴熳[1] 李鹏飞[1] 

机构地区：[1]华中科技大学同济医学院附属协和医院针灸科,湖北武汉430022

出　　处：《中国针灸》2015年第9期881-884,共4页Chinese Acupuncture & Moxibustion

基　　金：国家自然科学基金项目:81403485

摘　　要：目的:观察温针灸配合元素钙防治绝经后骨质丢失的临床效果,并探讨其作用机制。方法:将85例绝经后妇女随机均分为观察组(43例)和对照组(42例)。观察组与对照组每天睡前均口服钙尔奇D片1次,每次600mg,共服用1年。观察组取大杼、肾俞、悬钟穴,行温针灸治疗,每天1次,治疗30天为一疗程,疗程间隔60天,共治疗4个疗程。观察两组治疗前后腰椎及双侧髋关节骨密度、血清骨钙素(S-BGP)和尿羟脯氨酸(Hyp)与肌酐(Cr)比值(Hyp/Cr)。结果:1观察组治疗后能提高受试部位骨密度,前后比较差异均有统计学意义[腰椎:(0.811±0.024)g/cm2vs(0.892±0.019)g/cm2,股骨颈:(0.512±0.014)g/cm2 vs(0.554±0.015)g/cm2,股骨粗隆:(0.716±0.028)g/cm2 vs(0.769±0.026)g/cm2,Ward’s三角区:(0.590±0.013)g/cm2 vs(0.660±0.017)g/cm2,均P<0.05),且观察组较对照组提高明显(均P<0.05)。2对照组治疗后骨代谢指标明显升高,血清S-BGP、Hyp/Cr比值较观察组升高明显(均P<0.05)。结论:温针灸配合元素钙防治绝经后妇女骨质丢失效果显著,其可能的途径是通过降低绝经后妇女高转换骨代谢来实现的。Objective To observe the clinical effectiveness of warm needling combined with element calcium on postmenopausal osteoporosis,and to explore its action mechanism.Methods Eighty-five postmenopausal patients were randomly divided into an observation group（43cases）and a control group（42cases）.Both the two groups were treated with oral administration of caltrate-D tablet,600 mg per day,once a day before sleep for one year.Patients in the observation group were treated with warm needling at Dazhu（BL 11）,Shenshu（BL 23）,Xuanzhong（GB 39）,once a day;30days of treatment were taken as a course,and totally 4courses were given with an interval of 60 days between courses.The bone mineral density（BMD）of the lumbar vertebra and hip joint,and the level of serum bone gla protein（S-BGP）and hydroxyproline/creatinine（Hyp/Cr）were observed before and after treatment in the two groups.Results 1After treatment,the BMD in the observation group was significantly increased[lumbar vertebra（0.811±0.024）g/cm2 vs（0.892±0.019）g/cm2,femoral neck（0.512±0.014）g/cm2vs（0.554±0.015）g/cm2,femoral trochanter（0.716±0.028）g/cm2 vs（0.769±0.026）g/cm2,Ward＇s trigonum（0.590±0.013）g/cm2 vs（0.660±0.017）g/cm2,allP〈0.05）];the improvement in the observation group was more significant than that in the control group（allP〈0.05）.2After treatment,the index of bone metabolism in the control group was increased,and the serum S-BGP,the Hyp/Cr in the control group were higher than those in the observation group（bothP〈0.05）.Conclusion The treatment of warm needling combined with element calcium on postmenopausal osteoporosis is significant,which is likely to be achieved by reducing the bone metabolism of postmenopausal patients.

关 键 词：绝经后骨质丢失 温针灸 骨代谢 

分 类 号：R246.3[医药卫生—针灸推拿学]