昼夜节律与衰老的研究  

The research of biont in Circadian rhythms and aging degenerative process

作　　者：何本进[1,2] 梁庆华[1] 胡才友[1] 孙亮[2] 朱小泉[2] 原惠萍 杨帆[2] 李星慧[2] 秦娇琴[1,2] 贾春媛[2] 韩晶[2] 杜建财[2] 张翻弟 杨泽[2] 

机构地区：[1]广西壮族自治区江滨医院检验科,530021 [2]北京医院北京老年医学研究所,100730

出　　处：《中国老年保健医学》2015年第4期20-28,共9页Chinese Journal of Geriatric Care

基　　金：国家自然科学基金(81061120527;81370445;81472408;81400790);卫生部公益性研究基金(201302008);国家科技部十二五支撑计划(2012BAI10B01);北京市科技新星计划(Z121107002512058)

摘　　要：多数生物是以24小时或近似24小时为周期而显示出明显的昼夜节律。昼夜节律控制着觉醒与睡眠的更替,即使在全天照明或黑暗的环境条件下也照常运行。尽管在无光照条件下,昼夜节律也能自由运行,但光照对于该节律的设置调整则具有重要作用。通过温度改变、人工光照或人工黑暗条件,监测生物的生理、生化等活动是否会随昼夜节律的改变而发生变化。本文主要就纤细裸藻在温度或光照等条件的改变下,其细胞分裂周期、酶活性、芳香族氨基酸代谢等生理生化活性变化进行了综述。Most organisms exhibit clear circadian rhythm based on 24 h or approximately 24 h cycle. Circadian rhythm controls the replacement of wakefulness and sleep,it also runs normally even in light or dark condition throughout the day. However,circadian rhythm is also free-running under the condition of no light,and the setting of illumination to the rhythm plays a key role. Whether the physiological and biological activities of monitoring the organisms will change,following the variation of the circadian rhythm by changes in temperature,subjective light or dark conditions. We review the variations of physiological and biological activities of cell division cycle,enzymatic activity and aromatic amino acid metabolism in Euglena gracilis Klebs under the change of temperature or illumination condition.

关 键 词：纤细裸藻 昼夜节律 细胞分裂周期 昼夜振荡器 

分 类 号：R339.38[医药卫生—人体生理学]