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机构地区:[1]华侨大学化工学院,福建厦门361021 [2]中国医学科学院药物研究所,天然药物活性物质与功能国家重点实验室,北京100050
出 处:《中草药》2015年第15期2209-2211,共3页Chinese Traditional and Herbal Drugs
摘 要:目的研究紫薇Lagerstroemia indica茎叶的化学成分。方法通过硅胶、凝胶等柱色谱及高效液相色谱分离,根据理化性质和核磁共振波谱对化合物进行结构鉴定。结果从紫薇茎叶乙醇提取物中分离得到5个化合物,分别鉴定为1,2-二(3-羟基-4-甲氧基苯基)-3-氧代丙醇乙酸酯(1)、morusinol(2)、neocyclomorusin(3)、(+)-表丁香树脂醇-4-O-β-D-吡喃葡萄糖苷(4)、yunnanensin A(5)。结论化合物为1个新化合物,命名为紫薇乙酸酯A,化合物-为首次从该植物中分离得到。Objective To study the chemical constituents in the stems-leaves of Lagerstroemia indica.Methods The compounds were isolated and purified by silica gel,Sephadex LH-20 column chromatography,and HPLC.The structures of the compound were identified on the basis of chemical and spectral methods.Results Five compounds were isolated from the ethanol extract of the stems-leaves of L.indica and identified as 1,2-(3-hydroxy-4-methoxyphenyl)-3-oxopropyl acetate(1),morusinol(2),neocyclomorusin(3),(+)-episyring-4-O-β-D-glucopyranoside(4),and yunnanensin A(5).Conclusion Compound 1 is a new compound named lagerstroemiate A,and compounds 2-5 are isolated from this plant for the first time.
关 键 词:紫薇 紫薇乙酸酯A morusinol neocyclomorusin (+)-表丁香树脂醇-4-O-β-D-吡喃葡萄糖苷
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