双歧四联活菌片预防婴幼儿肺炎继发性腹泻的疗效和安全性  

EFFICACY AND SAFETY OF BIFIDOBACTERIUM TETRAVACCINE TABLETS IN PREVENTING SECONDARY DIARRHEA IN INFANTS WITH PNEUMONIA

作　　者：潘祥龙 

机构地区：[1]仪征市人民医院儿科,江苏仪征211400

出　　处：《承德医学院学报》2015年第5期380-382,共3页Journal of Chengde Medical University

摘　　要：目的探讨双歧四联活菌片预防婴幼儿肺炎继发性腹泻的疗效和安全性。方法:124例支气管肺炎患儿随机分为对照组和观察组,对照组患儿入院后接受常规对症治疗,观察组患儿在对照组常规治疗的基础上给予双歧四联活菌片。入院72h后记录两组患儿腹泻例数及腹泻情况,并统计比较两组患儿治疗中不良反应发生情况。结果:观察组继发性腹泻发生率为24.2%(15/62),对照组继发性腹泻发生率为40.3%(25/62),观察组患儿继发性腹泻发生率明显低于对照组(P<0.05)。两组患儿治疗中未见明显不良反应,患儿耐受性较好。结论:双歧四联活菌片可降低婴幼儿肺炎继发性腹泻的发生率,具有较好的安全性和较高的临床应用价值。Objective： To investigate the effi cacy and safety of Bifi dobacterium tetravaccine tablets in preventing secondary diarrhea in infants with pneumonia. Methods： 124 infants with bronchopneumonia were randomly divided into control group and observation group. The infants in control group received conventional symptomatic treatment; Besides conventional symptomatic treatment, the infants in observation group were also treated with Bifi dobacterium tetravaccine tablets. The incidence of diarrhea of infants in 2 groups 72 h after treatment was recorded, and the adverse reactions of infants in 2 groups during treatment were compared. Results： The incidence of diarrhea of infants in observation group was 24.2%（15/62）, which was obviously lower than that of control group（40.3%, P〈0.05）. There had no obvious adverse reactions during treatment of infants in 2 groups. Conclusions： Bifi dobacterium tetravaccine tablets can decrease the incidence of secondary diarrhea in infants with pneumonia, which has satisfactory security and fairly high clinical application value.

关 键 词：双歧四联活菌片 婴幼儿 支气管肺炎 继发性腹泻 疗效 安全性 

分 类 号：R725.6[医药卫生—儿科]