丙泊酚用于无痛肠镜检查对认知功能的影响  

EFFECTS OF PROPOFOL USED IN PAINLESS ENTEROSCOPE EXAMINATION ON COGNITIVE FUNCTION

作　　者：蔡健[1] 彭玉梅[2] 

机构地区：[1]太仓市中医医院麻醉科,江苏太仓215400 [2]无锡市第三人民医院麻醉科

出　　处：《承德医学院学报》2015年第5期385-386,共2页Journal of Chengde Medical University

摘　　要：目的:研究不同剂量丙泊酚用于门诊无痛肠镜检查对认知功能的影响。方法:90例肠镜检查患者随机均分为A、B、C三组。A组静注丙泊酚1.7mg/kg;其余两组在肠镜置入前静注芬太尼1μg/kg 2min后,B组静注丙泊酚1.7mg/kg,C组静注丙泊酚1mg/kg。全部患者于肠镜检查结束后5min行神经行为认知状态检查(NCSE),并在15min内完成。结果:90例患者均完成肠镜后NCSE测试。记忆能力测试和计算能力测试,C组的正确率均明显高于A组和B组(P<0.05)。结论:芬太尼1μg/kg加丙泊酚1mg/kg用于门诊无痛肠镜检查,不仅能提供满意的镇痛效果和检查条件,而且对认知功能无明显影响。Objective： To study the effects of propofol used in painless enteroscope examination on cognitive function. Methods： 90 patients scheduled for enteroscope examination were randomly divided into group A, B and C. The patients in group A were given propofol 1.7mg/kg. In group B and C, 2min after the patients were intravenously injected fentanyl 1μg/kg, then the patients were given propofol 1.7mg/kg and propofol 1mg/kg respectively. All the patients received neurobehavioral cognitive status examination（NCSE） test 5min after enteroscope examination and fi nished in 15 min. Results： All the 90 patients finished the NCSE test after enteroscope examination. In memory and calculation ability test, the accuracy rate of group C was obviously higher than that of group A and B（P〈0.05）. Conclusions： Fentanyl 1μg/kg combined propofol 1mg/kg used in painless enteroscope examination can provide satisfactory analgesic effects and check condition; Moreover, it has no obvious effects on cognitive function.

关 键 词：丙泊酚 无痛肠镜检查 认知功能 

分 类 号：R614[医药卫生—麻醉学]