代谢组学技术在儿科学的应用  

Application of Metabonomics Technology in Pediatrics

作　　者：周丽[1] 张万巧[1] 封志纯[1] 

机构地区：[1]北京军区总医院附属八一儿童医院代谢遗传实验室,北京100700

出　　处：《医学综述》2015年第17期3079-3081,共3页Medical Recapitulate

基　　金：国家自然科学基金(31100603)

摘　　要：代谢组学是将生物体(包括细胞、器官或个体)在不同条件下所产生的小分子代谢产物作为研究对象,是系统生物学研究的终端。作为生命科学研究的有力工具,其研究理念及相关技术已在生理学、诊断学、药理学、毒理学、营养学等多个领域得到应用。随着代谢组学技术的发展,越来越多的研究者将其应用于儿科学的研究。该文就代谢组学在儿科疾病病因探索、诊断、药物监测及儿童保健等方面的研究应用进行综述,探讨该技术在儿科学的应用前景。Metabonomics is the terminal of systemic biology, with micmmolecule metabolites as the research objects which are produced by organisms like cell, organ and individual under different conditions. As a powerful tool of life science research, the ideas and technologies of metabonomics have been applied in physiology, diagnosis, pharmacology, toxicology, nutrition and other fields. With the development of metabo- nomies, it has been more and more used in pediatrics as well. Hem is to make a review of the application of metabonomics in pediatrics on etiology, diagnosis, drug monitoring and child healthcare, and explore its fur- ther application.

关 键 词：代谢组学技术 儿科学 应用 

分 类 号：R72[医药卫生—儿科]