肥胖对男性精液影响的研究进展  

Research Progress in the Effects of Obesity on Male Semen

作　　者：白双勇[1] 王剑松[2] 

机构地区：[1]昆明医科大学研究生部,昆明650000 [2]昆明医科大学第二附属医院泌尿外科,昆明650101

出　　处：《医学综述》2015年第17期3087-3089,共3页Medical Recapitulate

基　　金：国家自然科学基金(81260374)

摘　　要：肥胖对男性精液质量的影响已经引起人们的重视,其机制一直是研究热点,目前发现肥胖通过降低男性游离睾酮水平,雌激素水平增加,抑制精子生成。同时精液中活性氧增加,导致精子DNA完整性降低,精卵结合及胚胎质量下降,最终使男性生育力降低。关于肥胖对男性精液质量影响的机制以及如何改变该影响还需要进一步研究。The effects of obesity on male semen quality has attracted people＇s attention,the research on the mechanisms of which has always been the focus. It＇s now found that obesity inhibits sperm generation by reducing the level of male free testosterone, increasing estrogen level. Meanwhile, the reactive oxygen species in semen increases, which results in lower sperm DNA integrity, and reduced sperm egg binding and embryo quality, ultimately affects male fertility. Further study is still needed for the influence mechanisms and how to reverse the influence.

关 键 词：肥胖 男性 精液 

分 类 号：R698.2[医药卫生—泌尿科学]