配型血小板输注在血液病患者中的应用  

The Application of Cross-matched Platelet in Patients with Blood Diseases

作　　者：叶静梅[1] 许志晟[1] 李翊泉[1] 李碧珊[1] 谭获[1] 

机构地区：[1]广州医科大学附属第一医院输血科,广州510230

出　　处：《血栓与止血学》2015年第4期232-234,共3页Chinese Journal of Thrombosis and Hemostasis

基　　金：广东省临床重点专科基金资助项目(20111219)

摘　　要：目的通过对比血小板配型前后血小板的输注效果,评估配型血小板在血液病患者中的疗效。方法以临床出血症状改善的情况、血小板计数增高指数(CCI)及血小板恢复百分率(PPR)为标准,对比配型前后血小板的输注效果。另外以临床输注血小板的次数分组,比较不同输注次数的患者出现血小板输注无效的差异。结果与配型前相比,配型血小板大大提高输注疗效(P<0.01),临床上输注5次血小板以上的患者比5次以下者出现血小板输注无效(PTR)的机率大大提高(P<0.01)。结论 PTR的出现与血小板输注次数有关。在出现PTR的血液病患者中使用配型血小板输注,可提高输注效果。Objective fusion refractoriness of blood cross- matched. Methods R To evaluate the clinical significance of platelets cross-matched on platelet transdiseases by comparing the efficiency of transfusion before and after platelets egarding the improvement of haemorrhage symptom, corrected count increment （CCI） , percent platelet recovery（PPR） as the standard, the efficiency of transfusion of before and after platelets cross- matched were compared. And comparing the difference of platelet transfusion refractoriness （PTR） by regarding on different times of platelet transfusion. Results Compare with before cross-matched, after crossmatched platelet transfusion was greatly improve curative effect （ P 〈 0.01 ）. And the more times of platelet transfusion （ ≥5 ）, the more probability of PTR was appearing （ P 〈 0.01 ）. Conclusion PTR was related to the number of platelet transfusion. Cross-matched platelet transfusionis an effective method in those patients refractory to random platelet transfusions. It should advocate to use cross-matched platelet in blood diseases.

关 键 词：血液病 血小板输注无效 血小板配型 

分 类 号：R457[医药卫生—治疗学]