驻闽2471名军队干部血尿酸现状及相关因素  

LEVELS OF BLOOD URIC ACID AMONG 2471 MILLTARY CADRES IN FUZHOU AND ITS RELATED FACTORS

作　　者：邓水秋[1] 施洪[1] 陈锦华[1] 周晓丹[1] 史超英[1] 杜立毅[1] 丁如平[1] 

机构地区：[1]南京军区福州总医院,福州350025

出　　处：《解放军预防医学杂志》2015年第4期378-380,共3页Journal of Preventive Medicine of Chinese People's Liberation Army

摘　　要：目的了解驻闽军队中青年干部人群高尿酸血症(HUA)的现状,并对其危险因素进行初步分析,为该人群HUA的防治提供依据。方法以2013年1-12月在某医院体检的2471名军队中青年干部为对象,测量指标包括身高、体质量、血压、血尿酸、血糖、胆固醇(TC)、甘油三酯(TG)和肌酐(Cr)等;比较HUA人群与正常人群上述指标的差异,采用单因素及多因素Logistic回归分析HUA的危险因素。结果驻闽军队中青年干部(HUA)患病率为27.1%,男性患病率(29.8%)明显高于女性(7.9%)。男性各年龄组血尿酸水平随年龄增长而明显增高。男、女性(HUA)组TC、TG、LDLC、Cr水平均明显高于正常组。多因素Logistic回归分析显示,肥胖、高血压、高甘油三酯、高胆固醇、肌酐的OR值分别为1.129、1.501、1.310、1.244、1.308,P<0.01;HDLC的OR值为0.494(P<0.01)。结论驻闽军队中青年干部HUA患病率较高,肥胖、高血压、高甘油三酯、高胆固醇、肌酐可能是HUA的危险因素,而HDLC可能为HUA的保护因素。Objective To investigate the prevalence of hyperuricemia （HUA） among young and middle -age military cadres in army stationed in Fuzhou, and to preliminarily analysis its risk factors, so as to provide evi- dence for the prevention and treatment of HUA. Methods A total of 2471 young and middle-age military caders who visited the Fuzhou General Hospital of Nanjing Military Region for medical examination from January to Decem- ber in 2013 were enrolled in this study. Height, weight, blood pressure, blood uric acid, blood glucose, cholester- ol, triglyeerides and ereatinine were recorded. The level of blood uric acid in different genders and age groups and the differences of biochemical markers between HUA group and the normal group were analyzed. Risk factors corre- lated with HUA were studied by logistic regression analysis. Results The prevalence of HUA was 27.1% in 2471 young and middle-age military cadres in army stationed in Fuzhou, 29.80 % of HUA for males was significantly higher than 7.86 % of that for females （P〈0.001）. The level of blood uric acid was increased with age in males （ P〈0.05 ）. The levels of cholesterol, triglycerides, LDLC, and creatinine in HUA group were higher than those in the normal group. Multivariate logistic regression analysis showed that the OR values of obesity, hypertension, high triglycerides, high cholesterol, ereatinine were 1. 129, 1. 501, 1. 310, 1. 244, and 1. 308 respectively （P〈0.01）, but OR value of HDLC was 0. 494 （ P〈0.01 ）. Conclusions The prevalence of HUA is high in young and middle- age military cadres from Fuzhou. Obesity, hypertension, high triglycerides, high cholesterol, and creatinine may be risk factors for HUA, while HDLC may be a protective factor for HUA.

关 键 词：军队中青年干部 高尿酸血症 患病率 危险因素 

分 类 号：R589.209[医药卫生—内分泌]