自制生肌膏对肛痈后创面愈合的影响  

Effect of self-made Shengji ointment on wound healing after anal carbuncle

作　　者：潘渊[1] 徐小平[1] 张磊[1] 陈冬[1] 刘兆辉[1] 

机构地区：[1]浙江省杭州市余杭区第一人民医院肛肠外科,浙江余杭311100

出　　处：《中国生化药物杂志》2015年第6期118-120,共3页Chinese Journal of Biochemical Pharmaceutics

摘　　要：目的探究术后使用自制生肌膏肛旁脓肿创面痊愈情况。方法将符合纳入标准的80例单纯性低位肛旁脓肿术后住院患者,采取随机数字表法随机分为对照组和治疗组,每组各40例。治疗组在肛周涂抹自制生肌膏并行纱布覆盖,对照组在肛周涂抹马应龙麝香痔疮膏并行纱布覆盖。采用VAS疼痛评分方法评估2组的疼痛情况并用肉芽组织评分标准评估肉芽生长状况。结果与第1天比较,2组用药后3、7、15 d VAS评分均降低(P<0.05);2组第1天VAS评分比较差异无统计学意义,治疗组第3、7、15天疼痛程度VAS评分均小于对照组(P<0.05)。治疗组平均疼痛持续时间短于对照组(P<0.05)。与第1天比较,2组用药后3、7、15 d肉芽组织评分均降低(P<0.05);2组第1天肉芽组织评分比较差异无统计学意义,治疗组第3、7、15天肉芽组织评分均小于对照组(P<0.05)。结论自制生肌膏对创面疼痛有明显缓解作用,对肉芽组织生长有明显促进作用,对于肛痈后促进创面愈合疗效优于马应龙麝香痔疮膏。Objective To study the clinical efficacy of self-made Shengji ointment on wound healing of postoperative perianal abscess. Methods 80 hospitalized patients with simple low anal abscess after surgery were randomly divided into control group and treatment group according to random digital table method, 40 cases in each group.The self-made Shengji ointment was smeared perianally and covered with gauze in treatment group, and Mayinglong shexiang zhichuang ointments was smeared perianally and covered with gauze in control group.VAS pain score and the granulation tissue scoring criteria were used to evaluate the growth status of the granulation.Results The VAS score in two groups were lower on the 3rd, 7th and 15th day than that on the 1st day （P〈0.05）;the VAS score on 1st day of two groups had no statisticall significant difference, but the VAS score in the treatment group were significantly lower than that in control group on the 3rd, 7th and 15th day, respectively （P〈0.05）.Duration of pain in treatment group was significantly lower than that of control group （P〈0.05）.The granulation tissue score in two groups on the 3rd, 7th and 15th day were lower than that on the 1st day,respectively （P 〈0.05）; the granulation tissue score on the 1st day of two groups had no statistically significant difference, but the granulation tissue score in treatment group on the 3rd, 7th and 15th day were significantly lower than that in control group, respectively（P 〈0.05）. Conclusion Self-made Shengji ointment could significantly relive the pain in wound, and promote the growth of granulation tissue, which has better effect in the treatment of wound healing of postoperative perianal abscess than Mayinglong shexiang zhichuang ointments.

关 键 词：自制生肌膏 肛旁脓肿 创面愈合 

分 类 号：R266[医药卫生—中医外科学]