降钙素原对细菌性痢疾患者病情评估的临床意义  

Clinical Significance of Disease Assessment on Bacterial Dysentery with Procalcitonin

作　　者：郭向东[1] 阿曼古[1] 曹丽[1] 闫鹏[1] 张荣[1] 安尼瓦尔[1] 

机构地区：[1]新疆生产建设兵团第一师医院感染性疾病科,阿克苏843000

出　　处：《新疆医学》2015年第8期1078-1081,共4页Xinjiang Medical Journal

摘　　要：目的探讨降钙素原(PCT)对细菌性痢疾患者病情评估的临床意义。方法统计分析71例细菌性痢疾患者的PCT及临床发热、腹泻、惊厥及病情程度等。了解PCT能否评估细菌性痢疾患者的临床病情。结果 71名患者的PCT阳性率为35.21%。PCT阳性组,22人发热,占88.00%;PCT阴性组,31人发热,占67.39%;两组差异具有统计学意义(p=0.03)。PCT阳性组最高体温为38.84±0.62℃,PCT阴性组最高体温为38.50±0.73℃,两组差异具有显著统计学意义(p<0.01),PCT阳性组发热持续时间为2.45±1.10天,PCT阴性组发热持续时间为1.67±0.65天,t=3.23,p<0.01。PCT阳性组中发热的<7岁儿童14名,有3名出现惊厥,PCT阴性组中发热的<7岁儿童19名,有1名出现惊厥,两组差异无统计学意义(p=0.15)。PCT阳性组腹泻持续时间为5.48±1.75天,PCT阴性组腹泻持续时间为5.43±1.68天,两组差异无统计学意义(p>0.05)。PCT阳性组中,病情重的有13例,PCT阴性组中病情重的有11例,两组差异具有显著统计学意义(p=0.01)。结论PCT可以作为细菌性痢疾患者病情评估的有效指标之一。Objective To investigate procalcitonin （PCT） to evaluate the clinical significance of the patients with bacillary dysentery. Methods Retrospective analysis 71 bacillary dysentery patient＇s PCT ,fever cases ,diarrhea , eelampsia and severity of disease. Results 71 patients＇ PCT positive rate was 35.21%. PCT positive group had 22 patients with fever, accounted for 88%; PCT negative group had 31 patients with fever （67.39%）. Statistically significant differences between the two groups（p=0.03）. The highest temperature in PCT positive group was 38.83 ± 0.62℃ and in PCT negative group was 38.50 - 0.73℃ ,there was a statistically significant difference between the two groups （p=0.01）; The fever time was 2.45 ~ 1.10d in PCT positive group and PCT negative group was 1.67 ± 0.65d, there was a statistically significant difference between the two groups （p〈0.01）; There are 3 convulsions in 14 Children aged less than 7 years old with fever in PCT positive group,and there was 1 convulsions in 19 negative PCT group with fever, there was no significant difference between the two groups （p=0.15）. The diarrhea time of PCT positive group were 5.48 ± 1.75d ,and negative PCT group were 5.43 ± 1.68d, there was no significant difference between the two groups （p〉0.05）. The severity of PCT positive group was 13 cases, in negative PCT group there were 11 cases of severe illness, there was a statistically significant difference between the two groups （p=0.01）. Conclusion PCT is one of the effective index can be used as bacterial dysentery patient assessment.

关 键 词：降钙素原 细菌性痢疾 发热 腹泻 病情评估 

分 类 号：R516.4[医药卫生—内科学]