小鼠早期胚胎发育过程中TGF-α和EGF-R mRNA的表达  

EXPRESSION OF TGF-α AND EGF-R mRNA IN THE EARLY EMBRYONIC DEVELOPMENT OF MICE

作　　者：严云勤[1] 谭景和[1] 张黎霞[2] 

机构地区：[1]东北农业大学生命学院,哈尔滨150030 [2]广东省农业科学院畜牧研究所,广州510001

出　　处：《动物学报》2002年第4期567-569,共3页ACTA ZOOLOGICA SINICA

摘　　要：This study was conducted to examine the activity of TGF α and EGF R mRNA using the RT PCR technique in the early embryonic development of the mouse. Expression of TGF α mRNA was initially observed in the 8 cell stage embryo of the mouse. The level of expression gradually increased in the morula and blastula. Expression of EGF R mRNA was initially observed in the 4 cell stage embryo of the mouse and 8 cell stage embryo;morula and blastula all expressed EGF R mRNA and the levels of expression had not changed. These results confirm that epidermal growth factors play a key role in early embryonic development of the mouse, especially TGF α which can stimulate and regulate embryonic development via the autocrine system.This study was conducted to examine the activity of TGF α and EGF R mRNA using the RT PCR technique in the early embryonic development of the mouse. Expression of TGF α mRNA was initially observed in the 8 cell stage embryo of the mouse. The level of expression gradually increased in the morula and blastula. Expression of EGF R mRNA was initially observed in the 4 cell stage embryo of the mouse and 8 cell stage embryo;morula and blastula all expressed EGF R mRNA and the levels of expression had not changed. These results confirm that epidermal growth factors play a key role in early embryonic development of the mouse, especially TGF α which can stimulate and regulate embryonic development via the autocrine system.

关 键 词：小鼠 早期胚胎发育过程 TGF-Α EGF-R MRNA 表达 

分 类 号：Q753[生物学—分子生物学]