布鲁菌病与其他菌属感染患者PCT、hs-CRP及白细胞检测结果对比分析  

Comparative analysis of PCT,hs-CRP and WBC tests results among patients with brucellosis and with other bacteria species infection

作　　者：苏群志[1] 唐荣德[1] 李洁云[1] 陈敏[1] 

机构地区：[1]江门市新会中医院检验科,广东江门529100

出　　处：《国际检验医学杂志》2015年第17期2505-2506,共2页International Journal of Laboratory Medicine

摘　　要：目的探讨降钙素原(PCT)、超敏C反应蛋白(hs-CRP)和白细胞检测在布鲁菌病诊断中的价值。方法将37例血培养阳性患者按感染菌属分为4组,并且检测PCT、hs-CRP和白细胞,然后将检测结果作对比分析。结果 4组患者的PCT和hs-CRP水平均升高,但布鲁氏菌组的升高程度低于其他3组,差异有统计学意义(P<0.05);布鲁氏菌组的白细胞总数(WBC)、中性粒细胞百分比(NEUT)和淋巴细胞百分比(LYMPH)均在正常范围内,而单核细胞百分比(MONO)升高检出率达80.0%。葡萄球菌组、肠杆菌组和链球菌组的WBC和NEUT高于布鲁氏菌组,LYMPH和MONO低于布鲁氏菌组,差异均有统计学意义(P<0.05)。结论 PCT、hs-CRP及白细胞检测可作为辅助布鲁菌病早期诊断的检测指标。Objective To investigate the diagnostic value of procalcitonin（PCT） ,high‐sensitivity C‐reactive protein（hs‐CRP） andwhitebloodcelltestsinpatientswithbrucellosis.Methods 37blood‐culturepositivepatientsweredividedinto4groupsac‐cording to the species of bacteria infected .In addition to that ,PCT ,hs‐CRP and white blood cell were tested and the tests results were compared .Results The PCT and hs‐CRP concentrations of the 4 groups all increased and while the increasing extent of bru‐cella group were lower than the other 3 groups ,the differences were statistically significant（P〈0 .05） .The counting of white blood cell（WBC） ,neutrophil（NEUT） and lymphocyte（LYMPH） were all in normal range while the monocyte（MONO） raised to 80 .0%in brucella group .WBC and NEUT apparently were higher in the other 3 groups than in brucella group ,while LYMPH and MONO were lower than brucella group ,the differences were statistically significant（P〈0 .05） .Conclusion The determinations of PCT ,hs‐CRP and white blood cell may act as the indicators for early stage of brucellosis .

关 键 词：布鲁菌病 降钙素原 超敏C反应蛋白 白细胞 

分 类 号：R516.7[医药卫生—内科学] R446.5[医药卫生—临床医学]