2型糖尿病中免疫异常的研究进展  

The research progress of immune disorders in type 2 diabetes mellitus

作　　者：朱蕴庆 胡蕴[1] 毛晓明[1] 

机构地区：[1]南京医科大学附属南京医院(南京市第一医院)内分泌科,210006

出　　处：《中国糖尿病杂志》2015年第9期859-861,共3页Chinese Journal of Diabetes

摘　　要：糖尿病的发病率逐年上升,引起人们越来越多的关注。研究表明,T2DM发病机制中存在慢性炎症和免疫调节异常,在一些患者中还发现了胰岛自身免疫的证据。因此,免疫调节治疗成为治疗T2DM的新思路。The incidence of diabetes mellitus is increasing year by year,which attracts more and more attention.Scientific researches have demonstrated the role of chronic systemic inflammation and immune dysregulation in the development of type 2diabetes mellitus（T2DM）.Moreover,the evidence of islet autoimmunity has also been identified in some patients with T2 DM.These discoveries highlight the potential of immune-modulatory therapies for T2 DM.

关 键 词：糖尿病 2型 细胞免疫 胰岛自身免疫 胰岛反应性T细胞 免疫调节 

分 类 号：R587.1[医药卫生—内分泌]