丝状真菌次级代谢产物的研究现状与发展趋势  

Research progresses and trends of secondary metabolites in filamentous fungi

作　　者：潘园园[1] 李二伟[1] 车永胜[1] 刘钢[1] 

机构地区：[1]中国科学院微生物研究所真菌学国家重点实验室,北京100101

出　　处：《菌物学报》2015年第5期890-899,共10页Mycosystema

基　　金：国家自然科学基金(31470177)

摘　　要：近年来,丝状真菌次级代谢产物的研究在国内外受到了极高的重视,同时也取得了较大的进展。本文对丝状真菌次级代谢产物的生物合成和调控机制以及隐性次级代谢产物生物合成基因簇的激活等方面进行了简述,同时对组合生物学给真菌次级代谢产物研究带来的机遇和挑战进行了讨论。In made great the fungal filamentous discussed recent years, the study of secondary metabolites in filamentous fungi has been paid more and more attention and progress. In this paper, we reviewed the recent research progresses on the biosynthesis, regulatory mechanisms of secondary metabolites and the activation of the cryptic secondary metabolites biosynthetic gene clusters in fungi. Opportunities and challenges on fungal secondary metabolites research from combinatorial biology are

关 键 词：丝状真菌 次级代谢 生物合成 调控 组合生物学 

分 类 号：Q936[生物学—微生物学]