肝泡状棘球蚴病边缘区域MR弥散加权成像与组织病理对照研究  

The correlation between MR DWI and pathology in peripheral zone of hepatic alveolar echinococcosis

作　　者：任波[1] 王静[1] 刘文亚[1] 张魏[1] 肖虎[1] 

机构地区：[1]新疆医科大学第一附属医院影像中心,乌鲁木齐830054

出　　处：《新疆医科大学学报》2015年第10期1213-1215,1219,共4页Journal of Xinjiang Medical University

基　　金：国家自然科学基金(81260232)

摘　　要：目的应用DWI及ADC值观察肝泡状棘球蚴病(HAE)的MR特征。方法 35例患者经MR常规扫描及DWI扫描,通过后处理工作站测量中心病变区域、边缘带和周边区域ADC值;对比分析病变在不同区域的ADC值和相应区域组织病理学之间的关系,探讨ADC值评价HAE病灶组织病理学特征的可行性;病灶标本行HE染色并测定微血管密度(MVD),分析病灶边缘带ADC值与MVD的相关性。结果 35例HAE病灶中心、边缘及外周区域的ADC值间的差异均有统计学意义(F=17.95、29.23,P均<0.05);ADC值与MVD无相关性(P=0.747、0.659);结论 DWI图像可以反映HAE病灶的组织异型性特征;病灶边缘区域的ADC值与同一区域的微血管密度(MVD)值无相关性。Objective Application of DWI and ADC to observe the characteristics of hepatic alveolar echino-coccosis （HAE）.Methods 35 patients underwent routine MR and DWI scan,through the post-processing workstation to measure the ADC values of center,peripheral area and surrounding zone of the lesion,analyzed the relationship in different areas of the ADC values and the histopathology.To explore whether the HAE histopathological characteristics as measured by ADC values.Focal line HE staining specimens and MVD of peripheral area of the lesion were analyzed.Results 35 patients HAE lesion center,peripheral area and surrounding zone of the ADC values differences were statistically significant （F =17.95,29.23,P 〈0.05）;ADC values has no correlation with MVD （P =0.747,0.659）;Conclusion DWI images can reflect the characteristics of the organization of peripheral area.No relationship was found between the ADC values and MVD of the same area of lesion.

关 键 词：泡球蚴 弥散加权成像 表观扩散系数 病理学 

分 类 号：R445[医药卫生—影像医学与核医学]