脑室腹膜分流术后表皮葡萄球菌感染的研究进展  

Ventriculoperitoneal shunt-related infections caused by Staphylococcus epidermidis

作　　者：乔潜林[1] 张保朝[1] 

机构地区：[1]河南省南阳市中心医院神经外科,473000

出　　处：《中华临床感染病杂志》2015年第4期371-375,共5页Chinese Journal of Clinical Infectious Diseases

摘　　要：脑室腹膜分流术后，表皮葡萄球菌常在分流管表面粘附聚集形成生物膜，生物膜包裹细菌，可以保护其免受宿主的攻击。由于存在生物膜、抗菌药物耐药、中枢神经系统的血脑屏障等因素，脑室腹膜分流术后表皮葡萄球菌感染的治疗非常困难。此文对脑室腹膜分流术后表皮葡萄球菌感染的易感因素与发生率、发病机制、治疗、预防等方面的进展进行综述。Staphylococcus epidermidis has the ability to adhere to the surface of shunt tube and to develop the biofilm .It can embed itself in the biofilm so as to escape from the defense of the host .Due to the presence of biofilms , antimicrobial drug resistance , blood brain barrier of central nervous system , the treatment of shunt-related infection caused by Staphylococcus epidermidis is very difficult.This paper reviews the risk factors , prevalence , pathogenesis , treatment and prevention of ventriculoperitoneal shunt-related infections caused by Staphylococcus epidermidis.

关 键 词：脑室腹膜分流术 葡萄球菌 表皮 中枢神经系统感染 

分 类 号：R651.1[医药卫生—外科学]