广西南宁856例学龄儿童血铅水平与5种必需元素的关系  

Correlation analysison levels of blood lead and five essential elements among 856 school-age children in Nanning of Guangxi

作　　者：李勇[1] 李牡艳[2] 陈静雯[1] 李少军[1] 袁宗祥[1] 莫玉焕 区仕燕[1] 陈国力[3] 黄明立[1] 姜岳明[1] 

机构地区：[1]广西医科大学公共卫生学院,广西南宁530021 [2]广西医科大学医学科学实验中心,广西南宁530021 [3]广西医科大学第一附属医院,广西南宁530021

出　　处：《工业卫生与职业病》2015年第5期330-333,共4页Industrial Health and Occupational Diseases

基　　金：国家重点基础研究发展计划-973计划(2012CB525001)

摘　　要：目的探讨广西南宁市856名6~14岁学龄儿童血Pb水平及其与Zn、Cu、Fe、Ga、Mg含量的关系。方法通过原子吸收分光光度法对856名6~14岁学龄儿童（男童601名,女童255名）血Pb、Zn、Cu、Fe、Ca、Mg含量进行测定,并对血Pb与Zn、Cu、Fe、Ca、Mg等含量进行相关性分析。结果学龄儿童血铅均值为（58.0±43.5）μg/L,铅中毒检出率为8.1%;儿童血铅水平和铅中毒率不同年龄组间比较,差异均无统计学意义（P〉0.05）;男童血Pb、Zn含量高于女童（P〈0.01,P〈0.05）;铅中毒组血Ca含量低于非铅中毒组（P〈0.05）。Pearson相关性分析显示,血Pb与血Ca呈负相关（P〈0.05）。结论南宁市学龄期儿童铅中毒情况仍然存在,体内铅过量可能会引起Ca代谢紊乱。Objective To investigate the blood lead（Pb）concentration（BLL）and the relationships with zinc（Zn）,copper（Cu）,iron（Fe）,calcium（Ca）and magnesium（Mg）among 856school-age children in Nanning,Guangxi.Methods Atomic absorption spectrophotometer was used for measuring blood concentrations of Pb,Zn,Cu,Fe,Ca and Mg from 856school-age children aged 6-14 years old（boys 601,girls 255）.Moreover,a correlation analysis on blood concentrations of Pb,Zn,Cu,Fe,Ca and Mg was made.Results The BLL in school-age children was 58.0±43.5μg/L,the prevalence rate of lead poisoning was 8.1%.There were no significant differences on BLLs or the prevalence of Pb intoxication in different age groups.Blood Pb and Zn in the boys were higher than that in the girls（P0.01,P0.05）.Ca concentration in the lead poisoning group was significantly down-regulated compared with the normal group（P〈0.05）.Pearson correlation analysis showed that blood Pb had a negative correlation with Ca（P〈0.05）.Conclusions The results suggested that school-age children still suffer from lead exposure,and excessive lead absorption can lead metabolic disorder of Ca in the body.

关 键 词：学龄儿童 血铅水平 金属元素 铅中毒 铅中毒检出率 

分 类 号：R179[医药卫生—妇幼卫生保健]