氧化应激在阻塞性睡眠呼吸暂停低通气综合征中的作用  

Role of oxidative stress in obstructive sleep apnea hypopnea syndrome

作　　者：苏艳娜[1] 张庆[2] 

机构地区：[1]承德医学院,067000 [2]承德医学院附属医院呼吸科,067000

出　　处：《国际呼吸杂志》2015年第17期1339-1342,共4页International Journal of Respiration

基　　金：国家十二五科技支撑计划课题（2012BA105802）

摘　　要：OSAHS是一种常见的呼吸系统疾病，能引起心脑血管系统、内分泌系统、神经系统等多系统损害，因此OSAHS更是一种系统性疾病。近年来有越来越多的研究证实OSAHS与氧化应激及多种埔炎性因子关系密切，本文旨在对其发病机制重新认识的基础上阐述OSAHS目前的抗氧化治疗现状。Obstructive sleep apnea hypopnea syndrome（OSAHS） is h common respiratory disease. It can cause serious complications of many systems, such as cardiovascular and cerebrovascular, endocrine and nervous systems. In a result, OSAHS is definitely a systemic disease. Recently a growing number of studies have comfired that OSAHS is closely connected with oxidative stress and a variety of inflammatory cytokines. Therefore,on the basis of renewed cognition of pathogenesis in OSAHS, the paper focuses on current status of antioxidatant treatment in OSAHS.

关 键 词：阻塞性睡眠呼吸暂停低通气综合征 系统性炎症反应综合征 氧化应激 活性氧自由基 抗氧化治疗 

分 类 号：R766.43[医药卫生—耳鼻咽喉科]