肾移植受者服药依从性与药物副反应的相关性研究  

Correlation research of medication adherence and symptom experience in adult kidney transplant recipients

作　　者：滕沙 彭晓[1] 林晓鸿[1] 张文馨[1] 尚雅彬 刘红霞[1] 

机构地区：[1]北京中医药大学护理学院,北京市100102

出　　处：《护理管理杂志》2015年第8期533-535,共3页Journal of Nursing Administration

基　　金：国家自然科学基金面上项目(81171860)

摘　　要：目的探讨肾移植受者服药依从性及其与药物副反应的相关性。方法采用患者一般资料调查表、服药依从性调查问卷、药物副反应症状调查表对312例肾移植受者进行调查。结果 84.94%的肾移植受者至少在某一方面存在不按医嘱服药的现象,不同年龄、性别、就业状况、经济负担、移植术后时间的肾移植受者服药依从性比较,差异具有统计学意义(P<0.01或P<0.05);肾移植受者服药依从性与药物副反应呈负相关(P<0.01)。结论了解影响肾移植受者服药依从性的相关因素,采取相应的干预措施提高其服药依从性,有助于移植物的长期存活。Objective To investigate the correlation of immunosuppression medication adherence and symptom experience in adult kidney transplant recip- ients. Methods A total of 312 renal transplant recipients were investigated with Adherence with Immunosuppressive Medication Scale and Symptom Experience of Immunosuppressive - related side effects Scale. Results About 84.94% of adult recipients had at least one aspect of nonadherence. Ages, ender, financial burden, post -time after transplantation, vocational status were influencing factors of medication adherence in adult kidney transplant recipients （P 〈 0. 01 or P 〈0.05）. Immunosuppression medication adherence was negatively correlated with symptom experience in adult kidney transplant recipients （P 〈 0.01 ）. Conclusion Understanding the relative factors of medication adherence and taking measures to improve medication adherence are beneficial to long - term survi- ving of kidney transplant recipients.

关 键 词：肾移植 受者 药物副反应 服药依从性 

分 类 号：R473.6[医药卫生—护理学]